Medicare National Coverage Determinations (NCD) Manual (Pub. 100-03), Ch. 1 § 20.21
Chelation Therapy for Treatment of Atherosclerosis
20.21 - Chelation Therapy for Treatment of Atherosclerosis
(Rev. 1, 10-03-03)
CIM 35-64
Chelation therapy is the application of chelation techniques for the therapeutic or
preventive effects of removing unwanted metal ions from the body. The application of
chelation therapy using ethylenediamine-tetra-acetic acid (EDTA) for the treatment and
prevention of atherosclerosis is controversial. There is no widely accepted rationale to
explain the beneficial effects attributed to this therapy. Its safety is questioned and its
clinical effectiveness has never been established by well-designed, controlled clinical
trials. It is not widely accepted and practiced by American physicians. EDTA chelation
therapy for atherosclerosis is considered experimental. For these reasons, EDTA
chelation therapy for the treatment or prevention of atherosclerosis is not covered. Some
practitioners refer to this therapy as chemoendarterectomy and may also show a diagnosis
other than atherosclerosis, such as arteriosclerosis or calcinosis. Claims employing such
variant terms should also be denied under this section.
Cross-reference: §20.22.