Medicare Claims Processing Manual (Pub. 100-04), Ch. 24 § 10.3
Scope of this Chapter
10.3 - Scope of this Chapter
(Rev. 13105; Issued- 04-10-25; Effective: 05-12-25; Implementation: 05-12-25)
This chapter will provide an overall description of EDI operations, requirements, roles
and responsibilities for Medicare FFS.
Medicare FFS is utilizing the following EDI transactions:
Transactions (Required Under HIPAA
Unless Otherwise Noted)
Current
Version
Short Reference
ASC X12 Health Care Eligibility Benefit
Inquiry and Response (270/271)
005010X279A1 ASC X12 270/271
eligibility transaction
ASC X12 Health Care Claim:
Professional (837)
005010X222A1 ASC X12 837
professional claim
ASC X12 Health Care Claim:
Institutional (837)
005010X223A2 ASC X12 837
institutional claim
ASC X12 Health Care Claim:
Dental (837)
005010X224A2 ASC X12 837 dental
claim
ASC X12 Interchange Acknowledgment,
TA1(not required under HIPAA)
005010X231A1 ASC X12 TA1
interchange
acknowledgment
ASC X12-Implementation
Acknowledgment For Health Care
Insurance (999) (not required under
HIPAA)
005010X231A1 ASC X12 999
implementation
acknowledgment
ASC X12 Health Care Claim
Payment/Advice (835)
005010X221A1 ASC X12 835 remittance
advice
ASC X12 Health Care Claim
Status Request and Response (276/277)
005010X212
ASC X12 276/277 claim
status; ASC X12 276/277
claim status request and
response; ASC X12 276
claim status request; ASC
X12 277 claim status
response
Transactions (Required Under HIPAA
Unless Otherwise Noted)
Current
Version
Short Reference
ASC X12 Health Care Claim
Acknowledgment (277) (not required
under HIPAA)
005010X214
ASC X12 277CA claim
acknowledgment
Telecommunication Standard,
National Council for Prescription Drug
Programs
D.0
Depending upon context:
NCPDP claim; NCPDP
transaction; other
functional NCPDP
designation
Batch Standard, National Council for
Prescription Drug Programs
1.2
Depending upon context:
NCPDP claim; NCPDP
batch transaction; NCPDP
transaction; other
functional NCPDP
designation
These administrative transactions require detailed instructions and specifications.
General instructions for the institutional and professional claim transactions, the NCPDP
transaction, as well as the error handling/acknowledgment transactions are provided
within this chapter. All other transactions have separate chapters dedicated to them.
The following IOM Publication 100-04, chapters provide more specific information on
the remaining electronic transactions. References to these chapters are provided below.
They can be accessed by going to
http://www.cms.gov/Regulations-and-Guidance/Guidance/Manuals/Internet-Only-
Manuals-IOMs.html and selecting Publication # 100-04.
1. Chapter 22 - ASC X12 835 remittance advice (includes information for paper
remittance advices)
2. Chapter 31 -ASC X12 270/271 eligibility benefit inquiry and response and ASC X12
276/277 claim status request and response
Two other related IOM chapters include:
Chapter 25 -Completing and Processing the Form CMS-1450 Data Set (includes
information related to ASC X12 837 institutional claims)
Chapter 26 -Completing and Processing the Form CMS-1500 Data Set (related to ASC
X12 837 professional claims)
Other sources of detailed information for each of these transactions are the Medicare FFS
Companion Guide documents and Medicare FFS edits documentation which can be
found at http://www.cms.gov/ElectronicBillingEDITrans/.