Medicare Claims Processing Manual (Pub. 100-04), Ch. 39 § 40
Practitioner Claims submission – A/B MAC (B)
40 - Practitioner Claims submission – A/B MAC (B)
(Rev. 13147; Issued: 03-28-25; Effective: 01-01-25; Implementation: 03-25-25)
Beginning January 1, 2020, claims for OTP services are submitted using the 837P transaction to
transmit health care claims electronically, or using the CMS-1500 (the paper version of the 837P).
Beginning January 1, 2021, OTPs may apply on the Medicare Enrollment Application for Institutional
Providers (CMS-855A) or through the Internet-based Provider Enrollment, Chain and Ownership
System (PECOS)(837I) when they enroll in the Medicare Program. These providers will submit
claims using the CMS-1450.
HCPCS codes G2067-G2069, G2073-G2077, G0137, and G0533 cover episodes of care of 7 continuous
days and cannot be billed for the same patient more than once per 7 continuous day period.
HCPCS codes G2076-G2080, G0137, and G0534-G0536 are add-on codes that are billed in addition to
one of the base bundle codes described by HCPCS codes G2067-G2069, G2073-G2077, and G0533.
Consistent with FDA labeling, HCPCS codes G2069 and G2073 should not be used more than once every
4 weeks.
HCPCS codes G2078 and G2079 may be billed in multiple units, up to 3 in one month (in addition to
the base bundle code).
HCPCS codes G2215, G2216, and G0532 are limited to being billed once every 30 days, however,
exceptions to this limit are allowed in the case where the beneficiary overdoses and uses the initial
supply of naloxone or nalmefene dispensed by the OTP to the extent that it is medically reasonable and
necessary to furnish additional naloxone or nalmefene. If an additional supply of naloxone or
nalmefene is needed within 30 days of the original supply being provided, OTPs must document in the
medical record the reason for the exception. HCPCS code G2216 (injectable naloxone) is contractor-
priced for CY 2021.
Patients may be appropriately given OUD services at more than one OTP within a 7 day period in
certain limited clinical situations, such as for guest dosing or when a patient transfers care between
OTPs. Each of the involved OTPs may bill the appropriate HCPCS codes for the services provided to
the patient, but both OTPs must maintain sufficient medical record documentation to reflect the clinical
situation and services provided.
In instances in which a patient is switching from one drug to another, the OTP should only bill for one
code describing a weekly bundled payment for that week and should determine which code to bill based
on which drug was furnished for the majority of the week.