Medicare Claims Processing Manual (Pub. 100-04), Ch. 3 § 90.5
Pancreas Transplants Kidney Transplants
Length: 1,228 wordsOfficial source
90.5 - Pancreas Transplants Kidney Transplants
(Rev.: 13757; Issued: 04-30-26; Effective: 04-01-26; Implementation: 04-06-26)
A. - Background
Effective July 1, 1999, Medicare covered pancreas transplantation when performed
simultaneously with or following a kidney transplant if ICD-9 is applicable, ICD-9-CM
procedure code 55.69. If ICD-10 is applicable, the following ICD-10-PCS codes will be
used:
0TY00Z0,
0TY00Z1,
0TY00Z2,
0TY10Z0.
0TY10Z1, and
0TY10Z2.
Pancreas transplantation is performed to induce an insulin independent, euglycemic state in
diabetic patients. The procedure is generally limited to those patients with severe secondary
complications of diabetes including kidney failure. However, pancreas transplantation is
sometimes performed on patients with labile diabetes and hypoglycemic unawareness.
Medicare has had a policy of not covering pancreas transplantation. The Office of Health
Technology Assessment performed an assessment on pancreas-kidney transplantation in
1994. They found reasonable graft survival outcomes for patients receiving either
simultaneous pancreas-kidney (SPK) transplantation or pancreas after kidney (PAK)
transplantation. For a list of facilities approved to perform SPK or PAK, refer to the
following Web site: https://www.cms.gov/Medicare/Provider-Enrollment-and-
Certification/CertificationandComplianc/downloads/ApprovedTransplantPrograms.pdf
B. - Billing for Pancreas Transplants
There are no special provisions related to managed care participants. Managed care plans are
required to provide all Medicare covered services. Medicare does not restrict which
hospitals or physicians may perform pancreas transplantation.
The transplant procedure and revenue code 0360 for the operating room are paid under these
codes. Procedures must be reported using the current ICD procedure codes for pancreas and
kidney transplants. Providers must place at least one of the following transplant procedure
codes on the claim:
If ICD-9 Is Applicable
52.80 Transplant of pancreas
52.82 Homotransplant of pancreas
The Medicare Code Editor (MCE) has been updated to include 52.80 and 52.82 as limited
coverage procedures. The shared system shall determine if the facility is approved for the
transplant and certified for either pediatric or adult transplants and Return To Provider (RTP)
as appropriate.
Effective October 1, 2000, ICD-9-CM code 52.83 was moved in the MCE to non-covered.
The contractor must override any deny edit on claims that came in with 52.82 prior to
October 1, 2000 and adjust, as 52.82 is the correct code.
If the discharge date is July 1, 1999, or later: the contractor processes the bill through
Grouper and Pricer.
If ICD-10 is applicable, the following procedure codes (ICD-10-PCS) are:
• 0FYG0Z0 Transplantation of Pancreas, Allogeneic, Open Approach
• 0FYG0Z1 Transplantation of Pancreas, Syngeneic, Open Approach
Pancreas transplantation is reasonable and necessary for the following diagnosis codes.
However, since this is not an all-inclusive list, the contractor is permitted to determine if any
additional diagnosis codes will be covered for this procedure.
If ICD-9-CM is applicable, Diabetes Diagnosis Codes and Descriptions
ICD-9-
CM
Code
Description
250.00
Diabetes mellitus without mention of complication, type II (non-insulin
dependent) (NIDDM) (adult onset) or unspecified type, not stated as
uncontrolled.
250.01
Diabetes mellitus without mention of complication, type I (insulin
dependent) (IDDM) (juvenile), not stated as uncontrolled.
250.02
Diabetes mellitus without mention of complication, type II (non-insulin
dependent) (NIDDM) (adult onset) or unspecified type, uncontrolled.
250.03
Diabetes mellitus without mention of complication, type I (insulin
dependent) (IDDM) (juvenile), uncontrolled.
250.1X
Diabetes with ketoacidosis
250.2X
Diabetes with hyperosmolarity
250.3X
Diabetes with coma
250.4X
Diabetes with renal manifestations
250.5X
Diabetes with ophthalmic manifestations
250.6X
Diabetes with neurological manifestations
250.7X
Diabetes with peripheral circulatory disorders
250.8X
Diabetes with other specified manifestations
250.9X
Diabetes with unspecified complication
NOTE: X=0-3
If ICD-10-CM is applicable, the diagnosis codes are: E10.10 - E10.9
Hypertensive Renal Diagnosis Codes and Descriptions if ICD-9-CM is applicable:
ICD-9-CM
Code
Description
403.01
Malignant hypertensive renal disease, with renal failure
403.11
Benign hypertensive renal disease, with renal failure
403.91
Unspecified hypertensive renal disease, with renal failure
404.02
Malignant hypertensive heart and renal disease, with renal failure
404.03
Malignant hypertensive heart and renal disease, with congestive heart
failure or renal failure
404.12
Benign hypertensive heart and renal disease, with renal failure
404.13
Benign hypertensive heart and renal disease, with congestive heart
failure or renal failure
404.92
Unspecified hypertensive heart and renal disease, with renal failure
ICD-9-CM
Code
Description
404.93
Unspecified hypertensive heart and renal disease, with congestive heart
failure or renal failure
585.1 - 585.6,
585.9
Chronic Renal Failure Code
If ICD-10-CM is applicable, diagnosis codes and descriptions are:
ICD-10-CM
code
Description
I12.0
Hypertensive chronic kidney disease with stage 5 chronic kidney
disease or end stage renal disease
I13.11
Hypertensive heart and chronic kidney disease without heart failure,
with stage 5 chronic kidney disease, or end stage renal disease
I13.2
Hypertensive heart and chronic kidney disease with heart failure and
with stage 5 chronic kidney disease, or end stage renal disease
N18.1
Chronic kidney disease, stage 1
N18.2
Chronic kidney disease, stage 2 (mild)
N18.3
Chronic kidney disease, stage 3 (moderate)
N18.4
Chronic kidney disease, stage 4 (severe)
N18.5
Chronic kidney disease, stage 5
N18.6
End stage renal disease
N18.9
Chronic kidney disease, unspecified
NOTE: If a patient had a kidney transplant that was successful, the patient no longer has
chronic kidney failure, therefore it would be inappropriate for the provider to bill ICD-9-CM
codes 585.1 - 585.6, 585.9 or, if ICD-10-CM is applicable, the diagnosis codes N18.1 -
N18.9 on such a patient. In these cases one of the following codes should be present on the
claim or in the beneficiary's history.
The provider uses the following ICD-9-CM status codes only when a kidney transplant was
performed before the pancreas transplant and ICD-9 is applicable:
ICD-9-
CM code
Description
V42.0
Organ or tissue replaced by transplant kidney
V43.89
Organ tissue replaced by other means, kidney or pancreas
If ICD-10-CM is applicable, the following ICD-10-CM status codes will be used:
ICD-10-
CM code
Description
Z48.22
Encounter for aftercare following kidney transplant
Z94.0
Kidney transplant status
NOTE: If a kidney and pancreas transplants are performed simultaneously, the claim should
contain a diabetes diagnosis code and a renal failure code or one of the hypertensive renal
failure diagnosis codes. The claim should also contain two transplant procedure codes. If
the claim is for a pancreas transplant only, the claim should contain a diabetes diagnosis code
and a status code to indicate a previous kidney transplant. If the status code is not on the
claim for the pancreas transplant, the contractor will search the beneficiary's claim history for
a status code indicating a prior kidney transplant.
C. – Drugs
If the pancreas transplant occurs after the kidney transplant, immunosuppressive therapy will
begin with the date of discharge from the inpatient stay for the pancreas transplant.
D. - Charges for Pancreas Acquisition Services
A separate organ acquisition cost center has been established for pancreas transplantation.
The Medicare cost report will include a separate line to account for pancreas transplantation
costs. The 42 CFR 412.2(e)(4) was changed to include pancreas in the list of organ
acquisition costs that are paid on a reasonable cost basis.
Acquisition costs for pancreas transplantation as well as kidney transplants will occur in
Revenue Center 081X. The contractor overrides any claims that suspend due to repetition of
revenue code 081X on the same claim if the patient had a simultaneous kidney/pancreas
transplant. It pays for acquisition costs for both kidney and pancreas organs if transplants are
performed simultaneously. It will not pay for more than two organ acquisitions on the same
claim. In addition, the contractor remove acquisition charges prior to sending the claims to
Pricer so such charges are not included in the outlier calculation.