Medicare Program Integrity Manual (Pub. 100-08), Ch. 3 § 3.4
Prepayment Review of Claims
3.4 - Prepayment Review of Claims
(Rev. 12772; Issued: 08-09-24; Effective: 09-20-24; Implementation: 09-20-24)
This section applies to MACs and UPICs.
A. General
Non-random (targeted) review is defined as review conducted with a specific reason or
logic to substantiate the cause for review. MACs are encouraged to initiate non-random
service-specific prepayment review to prevent improper payments for services identified
by CERT or Recovery Auditors or other sources.
The MACs shall initiate targeted provider-specific prepayment review only when there is
the likelihood of a sustained or high level of improper payments.
B. 100 Percent Prepayment Review and Random Review Instructions
Section 1302 of the Health Care and Education Reconciliation Act (HCERA) repealed
section 1874A (h) of the Social Security Act which had placed restrictions on prepayment
medical review. CMS review contractors shall comply with Section 1 random review and
Section 2 100 percent prepayment review.
1. Random Review
Random review is defined as review conducted without a specific reason or logic to
substantiate the cause for review. MACs have the discretion to conduct random reviews
of services; however, CMS does not recommend random reviews. MACs shall notify the
CMS Contracting Officer’s Representative (COR), Regional Office Technical Monitor
(TM), and Business Function Lead (BFL) of its intent to conduct random review. The
MAC shall describe what the intended result of the random review will be, an estimate of
the number of claims to be reviewed randomly and the rationale as to why random review
would be more effective than targeted review.
2. 100 Percent Prepayment Review
100 percent prepayment review is defined as review of every claim submitted by a
targeted provider for a specific code (i.e., DRG, CPT, HCPCs). 100 percent prepayment
review also includes review of every claim submitted by the targeted provider.
MACs have the discretion to conduct 100 percent prepayment review of providers. CMS
considers 100 percent prepayment review to be appropriate when a provider has a
prolonged time period of non-compliance with CMS policies. Any MAC that plans to
conduct 100 percent prepayment review shall inform the CMS COR, Regional Office
TM, and BFL in advance about any provider being placed on 100 percent prepayment
review. In addition, the MAC shall provide
• The background information on attempts to educate the provider.
• The historical improper payment rate of the provider before beginning 100
percent prepayment review.
• The length of time the provider is expected to be on 100 percent prepayment
reviews.
• The estimated number of claims and the dollar value of claims expected to be
reviewed per month.
• The criteria for removing the provider from 100 percent prepayment review.
3. UPIC Initiated Prepayment Reviews
No UPIC shall initiate a 100 percent prepayment review without CMS approval.
Therefore, the UPIC shall provide its COR and BFL a summary of the investigation, any
prior history (if applicable) with the provider/supplier in question, and any other relevant
information in a format agreed upon by the COR and BFL.
If the COR and BFL agree that 100 percent prepayment review is appropriate, the UPIC
shall include the case on the next case coordination meeting agenda for discussion and
final approval. During the case coordination meeting, the UPIC may receive additional
guidance from CMS related to subsequent actions related to these investigations. If the
UPIC has subsequent questions following the case coordination meeting, the UPIC shall
coordinate with its COR and BFL.