Medicare Program Integrity Manual (Pub. 100-08), Ch. 8 § 8.4.1.3
Steps for Conducting Statistical Sampling
8.4.1.3 - Steps for Conducting Statistical Sampling
(Rev. 11962; Issued: 04-21-23; Effective: 05-22-23; Implementation: 05-22-23)
The major steps in conducting statistical sampling are --
(1) Identifying the provider/supplier;
(2) Identifying the period to be reviewed;
(3) Defining the universe (target population) and the sampling unit, and constructing
the sampling frame;
(4) Assessing the distribution of the paid amounts in the sampling frame to determine
the sampling design; it is very likely that the distribution of the overpayments will not
be normal. However, there are many sampling methodologies (for example, use of
the Central Limit Theorem) that may be used to accommodate non-normal
distributions. The statistician should state the assumptions being made about the
distribution and explain the sampling methodology selected as a result of that
distribution.
(5) Performing the appropriate assessment(s) to determine whether the sample size is
appropriate for the statistical analyses used, and identifying, relative to the sample
size used, the corresponding confidence interval;
(6) Designing the sampling plan and selecting the sample from the sampling frame;
(7) Examining each of the sampling units and determining if there was an
overpayment or an underpayment; and
(8) Estimating the overpayment. When an overpayment has been determined to exist,
the contractor shall follow applicable instructions for notification and collection of
the overpayment, unless otherwise directed by CMS.
For each step, the contractor shall provide complete and clear documentation sufficient to
explain the action(s) taken in the step and to replicate, if needed, the statistical sampling.