10 C.F.R. § 26.133
Cutoff levels for drugs and drug metabolites.
Cite as 10 C.F.R. § 26.133 (2026)
Subject to the provisions of § 26.31(d)(3)(iii), licensees and other entities may specify more stringent cutoff levels for drugs and drug metabolites than those in Table 1 to § 26.133 and, in such cases, may report initial test results for only the more stringent cutoff levels. Otherwise, the following cutoff levels must be used for initial testing of urine specimens to determine whether they are negative or positive for the indicated drugs and drug metabolites:
Table 1 to § 26.133—Urine, Initial Test Cutoff Levels for Drugs and Drug Metabolites
Drugs or drug metabolites
Cutoff level
[nanograms
(ng)/mL]
Marijuana metabolites
50
Cocaine metabolites
150
Opioids:
Codeine/Morphine
1
2,000
Hydrocodone/Hydromorphone
300
Oxycodone/Oxymorphone
100
6-acetylmorphine (6-AM)
10
Phencyclidine (PCP)
25
Amphetamines:
2
AMP/MAMP
3
500
MDMA
4
/MDA
5
500
1
Morphine is the target analyte for codeine/morphine testing.
2
Either a single initial test kit or multiple initial test kits may be used provided the single test kit detects each target analyte independently at the specified cutoff.
3
Methamphetamine (MAMP) is the target analyte for amphetamine (AMP)/MAMP testing.
4
Methylenedioxymethamphetamine.
5
Methylenedioxyamphetamine.
[87 FR 71459, Nov. 22, 2022]
- Cross-references to the CFR
- 26.13326.31