21 C.F.R. § 556.113
Ceftiofur.
Cite as 21 C.F.R. § 556.113 (2026)
(a)
Acceptable daily intake and acute reference dose
—(1)
Acceptable daily intake (ADI).
The ADI for total residue of ceftiofur is 30 µg/kg of body weight per day.
(2)
Acute reference dose (ARfD).
The ARfD for total residue of ceftiofur is 0.830 mg/kg of body weight.
(b)
Tolerances.
The tolerances for desfuroylceftiofur (marker residue) are:
(1)
Cattle.
(i) Kidney (target tissue): 0.4 ppm.
(ii) Liver: 2 ppm.
(iii) Muscle: 1 ppm.
(iv) Milk: 0.1 ppm.
(2)
Chickens and turkeys.
Edible tissues (excluding eggs): Not required.
(3)
Goats.
(i) Kidney (target tissue): 8 ppm.
(ii) Liver: 2 ppm.
(iii) Muscle: 1 ppm.
(iv) Milk: 0.1 ppm.
(4)
Sheep.
Edible tissues (excluding milk): Not required.
(5)
Swine.
(i) Kidney (target tissue): 0.25 ppm.
(ii) Liver: 3 ppm.
(iii) Muscle: 2 ppm.
(c)
Related conditions of use.
See §§ 522.313a, 522.313b, 522.313c, and 526.313 of this chapter.
- Cross-references to the CFR
- 522.313a