21 C.F.R. § 556.500
Oxytetracycline.
Cite as 21 C.F.R. § 556.500 (2026)
(a)
Acceptable daily intake (ADI).
The ADI for total tetracycline residues (chlortetracycline, oxytetracycline, and tetracycline) is 25 µg/kg of body weight per day.
(b)
Tolerances.
The tolerances for the sum of tetracycline residues are:
(1)
Cattle.
(i) Muscle: 2 ppm.
(ii) Liver: 6 ppm.
(iii) Fat and kidney: 12 ppm.
(iv) Milk: 0.3 ppm.
(2)
Chickens and turkeys.
(i) Muscle: 2 ppm.
(ii) Liver: 6 ppm.
(iii) Fat and kidney: 12 ppm.
(3)
Finfish.
Muscle (with adhering skin when edible): 2 ppm.
(4)
Lobster.
Muscle: 2 ppm.
(5)
Swine and sheep.
(i) Muscle: 2 ppm.
(ii) Liver: 6 ppm.
(iii) Fat and kidney: 12 ppm.
(6)
Honey.
750 ppb.
(c)
Related conditions of use.
See §§ 520.1660c, 520.1660d, 520.1664, 522.1660a, 522.1660b, 522.1662, 522.1664, 529.1660, 558.450, and 558.455 of this chapter.
[84 FR 32993, July 11, 2019, as amended at 85 FR 18121, Apr. 1, 2020; 88 FR 16549, Mar. 20, 2023, 88 FR 55567, Aug. 16, 2023]
- Cross-references to the CFR
- 520.1660c