21 C.F.R. § 558.274
Hygromycin B.
Cite as 21 C.F.R. § 558.274 (2026)
(a)
Specifications.
Type A medicated articles containing 2.4 or 8 grams hygromycin B per pound (g/lb).
(b)
Sponsor.
See No. 058198 in § 510.600(c) of this chapter for as follows:
(c)
Related tolerances.
See § 556.330 of this chapter.
(d)
Special considerations.
(1) Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian. See § 558.6 for additional requirements.
(2) The expiration date of VFDs for hygromycin B medicated feeds must not exceed 6 months from the date of issuance. VFDs for hygromycin B shall not be refilled.
(e)
Conditions of use.
It is used in feed as follows:
(1)
Chickens
—
Hygromycin B grams/ton
Combination in grams/ton
Indications for use
Limitations
Sponsor
(i) 8 to 12
Chickens: For control of infections of large roundworms (
Ascaris galli
), cecal worms (
Heterakis gallinae
), and capillary worms (
Capillaria obsignata
)
Use in complete feed. Withdraw 3 days before slaughter
058198
(ii) [Reserved]
(2)
Swine
—
Hygromycin B grams/ton
Combination in grams/ton
Indications for use
Limitations
Sponsor
(i) 12
Swine: For control of infections of large roundworms (
A. suis
), nodular worms (
O. dentatum
), and whipworms (
Trichuris suis
)
In market hogs, use in complete feed for 8 weeks during the growing period. Withdraw 15 days before slaughter
058198
(ii) [Reserved]
[81 FR 95005, Dec. 27, 2016]
- Cross-references to the CFR
- 510.600556.330558.6