Criteria for Consideration of Additivity for Nonthreshold Toxic Substances

Section 352 Section 352.303  Criteria for Consideration of Additivity for Nonthreshold Toxic Substances Any combination of carcinogenic or otherwise nonthreshold toxic substances shall be assessed on a case by case basis. The Agency shall only consider such additivity for chemicals that exhibit the same type of effect and the same mechanism of toxicity, based on available scientific information that supports a reasonable assumption of additive effects.