105 CMR 365.004
Definitions
Active Tuberculosis. Tuberculosis is a state of active disease in any organ or tissue, with active
reproduction of Mycobacterium tuberculosis as determined by positive culture for
M. tuberculosis or a diagnostic nucleic acid or other definitive laboratory test (in distinction to
latent tuberculosis infection). The individual with active tuberculosis may or may not be
infectious.
Adherence. The extent to which a patient continues an agreed upon treatment plan for active or
clinically suspected tuberculosis, including taking anti-tuberculosis medications and keeping
health care appointments.
Adherence Support. Any measures or interventions that assist an individual in achieving
adherence with a regimen of treatment and care for tuberculosis. This may include, but is not
limited to, assistance with food and shelter, incentives, enablers, and substance abuse and mental
health treatment.
Case Assessment. The investigation conducted by the local board of health nurse to determine
the potential the patient has to transmit disease to others, based on level and duration of
exposure, and the medical, environmental, economic and social factors which may influence
adherence to the prescribed treatment plan.
Clinically Suspected Tuberculosis. A condition in which the individual has laboratory evidence
(smear or culture or other test) consistent with, but not confirmatory of, tuberculosis; or has chest
X-ray findings interpreted as probable tuberculosis by a qualified medical authority.
Communicable. The ability to transmit disease from one person or animal to another.
Confirmed Case of Tuberculosis. An individual who meets the Centers for Disease Control and
Prevention (CDC) criteria to verify a case as tuberculosis disease.
Contact. An individual who has been exposed to a person with communicable infectious
tuberculosis sufficient in both duration and proximity that there is increased risk for
transmission of tuberculosis.
Contact Investigation. The procedure of tracing, testing, evaluating, and treating persons who
have been in contact with a person who potentially has infectious tuberculosis.
Drug Resistant Tuberculosis. Tuberculosis caused by tubercle bacilli that are not susceptible to
one or more anti-tuberculosis drugs.
Enablers. A term used to describe those things that make it possible or easier for patients to
receive treatment by overcoming barriers such as transportation difficulties.
Incentives. Small rewards given to patients to encourage them to take their own medicines, keep
their clinic appointments, or follow their directly observed therapy plan.
(MA REG. # 1316, Dated 7-1-16)
Latent Tuberculosis Infection. Condition in which living Mycobacterium tuberculosis bacteria
are present in an individual as evidenced by skin test or other test for determining the presence
of tuberculosis infection. A person with latent tuberculosis infection does not have an illness and
is not infectious until and unless they develop active tuberculosis.
Nurse Case Manager. A registered nurse, designated by the local board of health, who has the
overall responsibility of monitoring and coordinating the implementation of the patient's
treatment plan until the completion of therapy. The nurse case manager also assists the patient
in obtaining other community resources, such as social services, that will assist him or her with
adherence to therapy.
Tubercle Bacillus/Bacilli.
A bacillus (bacteria) causing tuberculosis; usually refers to
Mycobacterium tuberculosis.
Tuberculosis Program. The program within the Department of Public Health that administers
the provisions of 105 CMR 365.000.
Tuberculosis Surveillance Nurse. A Public Health Nurse who works for the Tuberculosis