Appendix A

MASSACHUSETTS LIST OF INTERCHANGEABLE DRUGS Department of Public Healthregulation105 CMR720.050 describes the Massachusetts List of Interchangeable Drugs. 105 CMR 720.050(a) calls for the automatic adoption of all "A" rated drug products listed in the "Approved Drug Products with Therapeutic Equivalence Evaluations" and its supplements as published by the U.S. Food and Drug Administration (FDA), Department of Health and Human Services. This publication is commonly referred to as the "Orange Book". It is reprinted by the U.S. Pharmacopeial Convention Inc. (USP) as Volume III of the USP DI. 105 CMR 720.050(b) allows for the establishment of the Massachusetts Additional List of Interchangeable Drugs (Additional List), and provides the criteria upon which these drug products are approved. All prescriptions written by generic name can be interchanged if the drug is multi-source. To determine if a prescription written for a brand name drug product is interchangeable in Massachusetts: 1. Look up the drug product by the brand name in the index or by generic name in the "Approved Drug Products with Therapeutic Equivalence Evaluations" ("Orange Book"). The drug products are arranged alphabetically. 2. Compare the dosage form and strength of the drug product prescribed with the dosage form and strength of the same drug product in the "Orange Book". 3. If the same drug product, dosage form and strength has been assigned an "A" rating by FDA and is not listed on the Exception List contained within 105 CMR 720.050, the drug product is interchangeable. 4. If the drug product is not listed in the "Orange Book", refer to 105 CMR 720.050(b), the Massachusetts Additional List of Interchangeable Drugs (Additional List). 5. Look up the drug product by the generic name inthe Additional List. The drug products are arranged alphabetically. 6. Compare the dosage form and strength of the drug product prescribed with the dosage form and strength of the same drug product listed on the Additional List. 7. If the same drug product, dosage form and strength are listed, the drug product is interchangeable. Copies of the "Approved Drug Products with Therapeutic Equivalence Evaluations" and its supplements ("Orange Book") are available from the: U.S. Food and Drug Administration Department of Health and Human Services Government Printing Office Washington, D.C. 20402-9371 OPC 6768 (202) 783-3238 and www.fda.gov/cder/drug Copies of the USP DI (third volume of USP DI is the "Orange Book") are available from: The United States Pharmacopeial Convention, Inc., 12601 Twinbrook Parkway Rockville, MD 20852 (301) 881-0666 Copies of the Massachusetts Additional List of Interchangeable Drug Products (document number 105 CMR 720.000) are available from: The State House Bookstore Room 116 Boston, MA 02133 (617) 727-2834 and www.magnet.state.ma.us/dph/dcp/Drug Formulary/Drug Interchange TABLE OF CONTENTS Foreword Introduction Drug Product Problem Reporting Instructions Exception List Format of the Additional List NDA, ANDA, Applicant (name) Changes Abbreviations Massachusetts Additional List of Interchangeable Drugs (Alphabetical list of Official (Generic) Drug Names) Partial Proprietary Brand Cross-reference FOREWORD The Massachusetts List of Interchangeable Drugs, is prepared by the Drug Formulary Commission (DFC) and the Department of Public Health. The DFC is comprised of nine men and women appointed by the Governor for the express purpose of developing a list of those drug products that are safely interchangeable -- that is, equivalent to each other in all significant respects. The DFC was established by M.G.L. c. 17, § 13. This law was enacted with the intent of saving money for consumers ofprescription drugs, since drug products that are marketed under trademark or proprietary names are often available in the generic forms from competing manufacturers at substantially lower prices. M.G.L. c. 112, § 12D mandates prescription forms that allow practitioners to prescribe interchangeable drug products by simply signing the signature line. If a practitioner determines that a brand name drug product should be dispensed, he/she must sign the signature line and write the words "no substitution" in his/her own handwriting in the space provided below the signature line. The regulations call for the automatic adoptionof"A"rated drugproducts listed in the "Approved Drug Products with Therapeutic Equivalence Evaluations" and its supplements (commonly referred to as the "Orange Book") as published by the U.S. Food and Drug Administration, Department of Healthand Human Services, plus a list of additional drug products, the Massachusetts Additional List of Interchangeable Drugs ("Additional List"), individually reviewed and approved by the DFC and the Department. The regulations provide the criteria upon which the drug products listed on the Additional List are approved for interchange. The regulations also provide the DFC and the Department with the authority to review any "A" rated drug product listed in the "Orange Book" or drug product approved for interchange on the Additional List and delete it from the list of interchangeable drug products if deemed appropriate. Drug products assigned an"A" rating by FDA which are deleted from the Massachusetts List are placed on the Exception List. Drug products listed on the Additional List which are subsequently deleted are removed from the Additional List. Of the many factors considered by the Commission in determining which drugs to include on the List, equivalent safety and effectiveness are paramount. The Commission reviews evidence on bioequivalence and pharmaceutical equivalence and includes on the List only those drug products determined to be fully interchangeable and whose manufacturers are approved by the U.S. Food and Drug Administration. Practitioners may prescribe any drug that appears on the List with confidence that it is as safe and effective as its brand name counterpart. The efforts of the Commission in the assessment and evaluation ofdata and the preparationofthe List are to be commended. The Department presents the Massachusetts List of Interchangeable Drugs with pride and with confidence that the List will greatly benefit consumers throughout the Commonwealth. INTRODUCTION INTERCHANGEABLE (GENERIC) DRUG LAW In 1976 the Massachusetts Legislature passed an Act Further Regulating the Establishment of a Formulary of Interchangeable Drug Products (St. 1976, c. 470, § 13), commonly known as the Generic Drug Law. This law, enacted to promote and regulate the use of generic drugs, created the Drug Formulary Commission to develop a list of interchangeable drug products and also required the use of a standard prescription form to encourage practitioners to prescribe generic drugs. PRESCRIPTION FORM M.G.L. c. 112, § 12D mandates prescription forms with one signature line. Ifthe prescriber signs the prescription form and writes the words "no substitution" in his/her own handwriting in the space provided below the signature line, the pharmacist must fill the prescription exactly as indicated, with no interchange permitted. However, if the prescriber signs the prescription and does not write "no substitution" under his/her signature, the pharmacist is legally required to dispense a less expensive, equivalent interchangeable drug product listed in the Massachusetts List of Interchangeable Drugs if one is reasonably available. MASSACHUSETTS LIST OF INTERCHANGEABLE DRUGS The Massachusetts List of Interchangeable Drugs (MLID) consists of the "A" rated drug products listed in the "Approved Drug Products with Therapeutic Equivalence Evaluations" and its supplements as published by the U.S. Food and Drug Administration, Department of Health and Human Services ("Orange Book") and the Massachusetts Additional List of Interchangeable Drugs (Additional List). The Additional List is developed by the Drug Formulary Commission. The Commission determines drug products to be interchangeable only when they meet certain criteria: (a) the drug product is available from more than one source, with the same active ingredient in the same dosage form and strength; (b) its manufacturer is approved by the U.S. Food and Drug Administration (FDA); and (c) when essential to therapeutic outcome, the manufacturer of the drug has documented clinical evidence of bioequivalence. The Commission judges that all the drugs included on the MLID meet these standards and are bioequivalent, if essential, based on assessment and evaluation of the U.S. Pharmacopeia and its supplements, other state and hospital formularies, listings of the U.S. Department of Health and Human Services of the FDA, and on the expertise of its members. The List does not include: (a) drugs that are protected by patent rights or available from only one source; (b) many controlled-release and enteric coated drug products since they may not consistently deliver the same quantities of their active ingredients; (c) those drugs for which the Commission had any significant doubt about safe interchange between manufacturers; and (d) any drug for which bioequivalence is considered essential but for which bioequivalence has not been demonstrated or an appropriate standard for bioequivalence has not been established. Bioequivalence is determined to be necessary for a particular drug when bioinequivalence might result in therapeutic failure or hazard to the patient. Bioequivalent drug products do not show a significant difference in the rate and extent ofabsorptionwhenadministered at the same dosage under similar conditions. Drugs that are equivalent in the extent to which they are absorbed into a patient's body that differ in the rate of absorption may be therapeuticallyequivalent -- havingthe same medical effect -- either because the rate of absorption is not essential to the attainment of effective body concentrations of the drug, or because the difference in the rate is otherwise considered medically insignificant. Bioequivalence is a primary consideration for those drug products with a narrow therapeutic/toxic dosage range (when variation in the rate orextentof absorption could have a critical effect) where careful determination of the correct dosage and monitoring ofthe patient is essential to safe and effective use. To determine for which drugs bioequivalence is essential, the Commission relies on expert medical testimony, studies done by the pharmaceutical industry, the knowledge and expertise of the individual members of the Commission, and advice from the FDA. All drug products manufactured by FDA approved firms are considered safe and effective for their intended use, even if the product has not been included in the MLID. A practitioner may begin a patient's therapy with a drug product from any manufacturerwho hasbeenapproved by the FDA, even though interchange of the drug once the dosage has been calculated for the individual is not advised. Several generic drug products are manufactured under the same new drug application (NDA) as the brand name drug products. According to section 1.6 of the Orange Book, drug products with the same NDA are therapeutically equivalent. Massachusetts regulations allow the interchange of these products. Distributors or repackagers of drug products manufactured under the same NDA as the brand name product are not identified in the Orange Book. Pharmacists who may not be able to determine if drug products are interchangeable should contact the manufacturers, distributors or repackagers. In addition the Department maintains an unofficial list of these products. Information relative to the Interchangeable (Generic) Drug Law may be obtained from the Department of Public Health, Division of Food and Drugs, 305 South Street, Jamaica Plain, MA 02130, telephone number (617) 727-2670, and fromtheBoards ofRegistrationin Medicine, Dentistry and Pharmacy. DRUG PRODUCT PROBLEM REPORTING INSTRUCTIONS Since 1971 the United States Pharmacopeia (USP), in cooperation with various professional associations and the Food and Drug Administration (FDA), has operated the Drug Product Problem Reporting Program. This program can be utilized by pharmacists, physicians, or consumers to report any product problems encountered when using drugs interchanged under the Massachusetts generic drug law. The program is product oriented, and patient identification not requested. Should you prefer to remain anonymous, so indicate to the USP and your name will be withheld from the manufacturer and the FDA. Your participation in reporting problems will help to ensure that the drug products prescribed and dispensed in Massachusetts are of continued high quality. Reports should be sent to The United States Pharmacopeial Convention, Inc., 12601 Twinbrook Parkway, Rockville, MD 20852, (301) 881-0666. The USP is an impartial, non-governmental organization concerned with drug standards and quality control. After USP receives a report, copies are forwarded to the FDA and to the manufacturer of the product involved. Either the FDA or the manufacturer may act to investigate or correct problems. EXCEPTION LIST Orange Book "A" rated drug products not approved for interchange. There are currently no products designated to be listed on the Exception List. ADDITIONAL LIST The Massachusetts Additional List of Interchangeable Drugs (Additional List) has been printed in a format designed to be concise and understandable. Interchangeable drugs are listed alphabetically according to their official (chemical or generic) names, and separate sections in each listing show dosage forms, strengths, FDA approved manufacturers, and categories. DRUG Drugs are listed in alphabetical order by their generic names and are printed in capital letters. Drug products containing more than one active ingredient (for example, CODEINE PHOSPHATE, GUAIFENESIN) are listed in the conventional order of ingredients. Only drug products grouped under single headings are to be interchanged. DOSAGE FORM Under the generic names are listed the various multisource dosage forms in which a drug product is available. Abbreviations used for dosage forms and approved manufacturers are found in the front of the Additional List. Only identical dosage forms and strengths of identical drugs are to be interchanged. STRENGTH The approved strengths of the drug products are listed under the heading "Strength(s)." The "strengths" must be read along with the "dosage forms" since any strength shown is available only for the dosage form directly to its left. Dosage strength is in metric units that are sometimes rounded off from apothecary measures, which may introduce slight variations in the strength of certain products. Single ingredient drug product strengths are separated by commas. Combination drug products have a slash separating the strengths of the individual ingredients. If more than one strength of a single component of a combination drug product is approved, they will be separated by commas. For example, the strength of a tablet of aspirin with codeine phosphate is "325mg / 15mg, 30mg, 60mg" which means that the combination is available with 325 milligrams of aspirin and 15, 30, or 60 milligrams of codeine phosphate. Drug products with three or more components have their active ingredients listed individuallyinparentheses and have slashes separating the strengths of the individual ingredients. MANUFACTURERS Next to the heading "Manufacturers" are all approved manufacturers for the drug product in that group, listed by three letter abbreviations in capital letters. (See list of manufacturer abbreviations in front of the Additional List.) Listed manufacturers have met all legal requirements, including compliance with the FDA Good Manufacturing Practices for the production of the drug product indicated. Approved manufacturers hold current new drug applications (NDAs) or abbreviated new drug applications (ANDAs) when required by law. NDA, ANDA APPLICANT (NAME) CHANGES Because it is not practical to identify in the Massachusetts Additional List of Interchangeable Drugs (Additional List) each and every product involved when an applicant transfers its entire line of approved drug products to another applicant, or when an applicant changes its name, these transfers and name changes are identified in this section. In addition, the new manufacturers are listed in parenthesis beside the original manufacturer under the Manufacturers' Abbreviations section of the Additional List. Where only partial approved product lines are transferred betweenapplicants, each approved product involved will appear with the manufacturer name change in the Additional List amendment. Previously listed name changes have been incorporated into the revised Manufacturers’ Abbreviations section. ABBREVIATIONS The following abbreviations are used in the Massachusetts List of Interchangeable Drugs. DOSAGE FORMS aero aerosol ml milliliter amp ampule oint ointment cap capsule ophth ophthalmic conc concentrate oral gran oral granules for e.c. enteric-coated reconstitution elix elixir oral powder oral powder for g gram reconstitution Hbr hydrobromide oral sol oral solution HCl hydrochloride pow powder HC hydrocortisone sol solution inhl inhalation SR sustained release inhl liquid inhalation liquid subl tab sublingual tablet inhl sol inhalation solution supp suppository inj injection susp suspension irr sol irrigating solution syr syrup I.U. international units tab tablet liq liquid top aero topical aerosol lot lotion top swab topical swab mcg microgram U units mEq milliequivalents vag vaginal mg milligram MANUFACTURERS' ABBREVIATIONS 3MP 3M Pharmaceutical Inc AAA Alpha Therapeutic ARC Arcola Labs. ABB Abbott APC Arcum Pharmaceuticlal Corp. ABI Abic ARP Armenpharm ABL Able Laboratories ARM Armour Pharmaceuticals ACI ACIC Limited ASC Ascot Hospital Products ACP Advanced Care Prod. ASA Asta ADV Advanced Remedies ASP Astra Pharmaceuticals LP AGV Agvar Chemicals ATH Athena Neurosciences AKO Akorn BAK Baker Norton AKZ Akzona Inc. BAN Banner Pharmacaps ALC Alcon Labs BAP Barlan Pharmacal ALL Allergan Pharmaceuticals B/I Boehringer Ingelheim ALI Alliance Pharmaceutical B/M Boehringer Mannheim. Ther. Div ALP Alpharma BAR Barr Labs APP Alphapharm Party BAS Basel Pharmaceuticals ALT Altana BAT Bartor ALZ Alza Corp. B&L Bausch & Lomb ALR Alra Laboratories BAY Bayer Corp AMA Amaric BEA Beach Prod. AMB Ambix Labs B-D Becton,Dickinson & Co. ACC American Cyanamid Co. BED Bedford Laboratories AHP American Home Products BEL Bell ARL American Regent Labs. BDP Beta Derm Pharmaceuticals AME Amersham BER Berlex AMG Amgen BFA B.F. Asher AMI Amide Pharmaceuticals BHC B.H. Chemicals AMT American Therapeutics BID Biodevelopment ANA Anabolic BIO Bio Technology General ANB Anbex BIV Biovail ANC Angus Chemical BLA Blairex Laboratories ANE Anesta BLO Block Drug Co. ANG Angelini APO Apothecon APK Apothekernes APP American Pharmaceutical Partners BLU Bluline BRL Blue Ridge Laboratories BOC Bock Pharmacal BOW Bowman Pharm. BMS Bristol Myers Squibb BRC Bracco Diagnostics BRD Bradley Pharm. BRA Braintree Laboratories BRI Bristol-Myers Prod. BTG BTG Pharmaceuticals BVL Ben-Venue Labs BYR Byron Chemical C&M C & M Pharmacal CAD Cadema Medical Products CAG Calgon Corp. CDC Carderm Capital C-P Chesebrough - Ponds C-W Cook - Waite C/C Chase Chemical CSL Chase Laboratories C/P Corvit Pharmaceuticals CAL Carlisle CAM Camall CAR Carnick Labs CTW CarterWallace CEN Century Pharmaceuticals CBV Cetus Ben Venue Therapeutics CHA Chamberlin Parenteral Corp. CHE Chelsea Laboratories CHM Chemed Corp. CVO Ciba Vision Ophthalmics CIR Circa Pharmaceuticals CJD Copanos, J.D. CLA Clay - Park CLO Clonmel Healthcare CMB C.M. Bundy CMC Consolidated Midland Corp. C/T Controlled Therapeutics CMP Carolina Medical Products CNC H.R. Cenci COL Colgate Palmolive COM Combe CON Connaught Laboratories COO Cooper Labs COP Copley Pharmaceutical CPG Consolidated Pharmacy Group CRE Creighton Products CUM Cumberland Swan CUR Curatex Pharmaceuticals CTL Central Pharmacal D&G Davis & Geck D/L DPT Laboratories D-R Del-Ray Laboratories Inc. DAN Danbury Pharmacal DAR Darby Group Companies DEL Dell DEP Deproco DER Dermik Laboratories DES Deseret Medical DEY Deylabs DHL DHL Laboratories DIA Dial Corp. DIS DMD DMG DOW DPT DPM DUR DUN DYN E/K EAT ECR ELA ELL EMP END EON ENQ ENZ ESR ERS ESI ESP ETH ETX ETK EVY EZC FAU FER FRT FRR FIS FLE FOR FOU FOY FRE G&W GAL GEI GEC GED GET GEP GEV GES GEZ GIL GLD GLW GLE GLO G/P GOL GRE GRI G/L GUA GYM GYN H-R Dista Duramed D M Graham Laboratories Dow Pharmaceutical Dupont Pharmaceuticals Dupont Merck Dura Pharmaceuticals Dunhall Dynapharm Eastman Kodak Eaton Medical Corp. ECR Pharmaceuticals Elan Pharmaceuticals Ellis Pharmaceuticals EM Pharma Endo Eon Laboratories Enquay Pharm Enzon Elkins-Sinn/AH Robins Ersana ESI Lederle Generics ESI Pharmacal Ethicon Inc. Ethex Ethitek Pharmaceuticals Everylife E Z EM Co. Faulding Pharm. Co. Ferndale Ferrante Ferring Labs Fisons Fleming & Co. Forest Fougera Foy Fresenius G & W Galderma Geigy Gencon Genderm Genentech Genpharm Geneva Gensia Sicor Pharmaceuticals Inc Genzyme Gilbert Laboratories Glades GlaxoWellcome Glenwood Global Pharm. Golden Pharms. Goldine Greenstone Griffen,KW Gruppo Lepetit Guardian GYMA Laboratories Gynopharm Holland-Rantos HAL Halsey Labs LEO Leo Pharms HAM Hamilton Pharmaceuticals LIF Life Labs HAN Hnford GC LIL Lilly HEA Heather LIP Liposome HEN Heran Pharmaceutical LIQ Liquipharm HEX Hexcel Chemical Products LNK LNK International HER Hermal Pharmaceutical LOC Loch Pharmaceuticals HIC Hickam LOR Lorex H/D Hill Dermaceuticals LOT Lotus Biochemical HIR Hirsch Industries LPI LPI Holding HIT Hi Tech Pharma LUI Luitpold HTP High Technology Pharmacal LUS Lek USA Inc. HLC Halocarbon LYN LYNE Laboratories HCC Hoechst Celanese Corp. M/P Mallinckrodt Pharmaceutical. HMR Hoechst Marion Roussell MAY Mayrand HOE Hoechst-Rousel MAT Matrix Labs HOR Horus Therapeutics MCG Mcgaw HOY Hoyt MCN McNeil Consumer Products HUD Hudson Pharmaceuticals MDP MD Pharmaceuticals HUN Huntington MEA Mead Johnson HYB Hybritec Inc. MJN Mead Johnson Nutritionals HYG Hygenics M/R Medco Research HYR Hyrex MVA Medeva IMM Immunex MEP Medics Pharmaceuticals IMP IMP Inc. MPI Medi Physics, Inc. ICN ICN Pharmaceuticals MAG Mepha AG IMS International Medication MER Mericon INP Interpharm MET Metronic INV Invamed, Inc. MGI MGI Pharma INW Inwood Labs MID Midway Medical ICC Interchem Corp. MIK Mikart Laboratories ILC International Latex Corp. MIS Mission Pharmacol ING Ingram Pharmaceutical MJP MJ Pharmaceuticals INH Inhalon MKL Moore Kirk Labs IOL Iolab MLI Marchar Laboratories IOM Iomed MLP Miller Pharmacal IPR IPR Pharm MLX Milex IVA IVAX MMD Marion Merrell Dow J&J Johnson & Johnson MOR Morton Grove JAC Jacobus MCK Merck & Co. JAN Janssen Pharmaceuticals MSM Marsam JER Jerome Stevens Labs MSL Marshall Pharmacal JRW Johnson RW MTC Martec JON Jones Pharma Inc MOV Mova KAL Kalapharm MUR Muro KBP Kabi Pharmacia MUT Mutual Pharmaceuticals KEE Keene MYL Mylan Pharmaceuticals KED Kendall NEP Nephron Pharmaceuticals Inc KEN Kenwood NEU Neutrogena KIN King Pharmaceuticals NOR Norbrook Laboratories KIR Kirkman Sales N/W Norton Waterford KNO Knoll N/N Novo Nordisk KPI Key Pharmaceuticals NEW Newtron Pharmaceuticals KVP KV Pharmaceutical Co. NHN Norton HN L/F Labs Fournier NOV Novocol L/A Laboratories Atral NVP Novopharm Ltd. LAF Lafayette Pharms NUM Numark LAN Lannett NYC Nycomed LED Lederle NYL Nylos Trading LEI Leiras ORI Organon, Inc. LEK Lek Ljubliana OCL Oclassen LEM Lemmon OHM OHM Laboratories OMD Ohmeda Pharmaceutical OSA On Site Azla ODC Ormont Drug & Chemical OPC Ortho Pharmaceuticals OPT Optopic Laboratories Corp. ORG Organics OAP Otsuka America Pharmaceutical PAK Pal-Pak PAL Palisades P/D Parke Davis P/I Plantex/Ikpharm P/K Purepac-Kalipharma P/P Parmed Pharmaceuticals PAC Paco Research PAD Paddock Labs PHD Pharmaderm PAN Panray PAR Par PNL Parnell PER Perrigo PCE Pharmachemie PHC Pharmics PHK Pharmakinetics Labs PHM Pharmeral PHO Phoenix Labs PHS Pharma Serve PHT Pharmaton PFF Pfeiffer PFI Pfizer P/U Pharmacia & Upjohn P/A Pharmaceutical Association PIO Pioneer Pharmaceutical Inc. PPI Physicians Products Inc. PSA Pharmaceutical Specialist Assoc POH Pohl Boskamp POL Polymedia PGP Prographarm PRD Professional Disposables PRO Proter Laboratory PRI Private Formulations P&G Proctor & Gamble PRV Pharmavite PTK Pharma-Tek PUF Purdue Frederick PUR Purepac QUA Quantum Pharmics Ltd. QLT QLT PhototherapeuticsInc. RAN Ranbaxy Pharmaceuticals R/C Reckitt & Colman R&C Reed & Carnrick R/I Research Industries RXP Rexar Pharmacal RAC Rachelle Labs REN Ren-Pharm Internatl. Ltd. RHP Rhone - Poulenc RPR Rhone-Poulenc Rorer RAH Robins, A.H. REX Rexall/Sundown RIC Richlyn Labs ROC Roche Labs. RPF Roerig/Pfizer ROA Roaco RBP ROR ROS ROX ROY RPC RUG S-M S/W S/L SAK SAV SAN SCE SPI SCH S/P SWZ SZG SCI SCS SEA SER SEQ SHM SHI SID SIG SIX SKB SBH SOL SLV SOM SBM SDP STI STL STR STS STZ SUP SPP SUR SYN SYO TAB TAG TAK TAP TAR TAY TEC THE THK THA TIC TOP T/L TOR UDL UMD Roberts Pharmaceutical Rorer Ross Labs Roxane Labs Royce Laboratories Rosemont Pharmaceutical Corp. Rugby Labs Spencer-Mead Sanofi Winthrop Schmid Laboratories Sankyo Savage Labs/Altana Sandoz Scherer, R.P. Schein Pharmaceutical, Inc. Schering Corporation Schering/Plough Schwarz Pharma SchwarzGMBH ScinoPharm International SCS Pharmaceuticals Searle Serono Laboratories Sequus Pharmaceuticals Sherwood Medical Shionogi USA Sidmak Laboratories Sigma Tau Silarx Smith, Kline Beecham Sola Barnes Hind Solopak Laboratories Solvay Somerset Sorin Biomedics Sperti Drug Products Steifel Stanlabs Pharmaceutical Co. Star Pharmaceuticals Steris Laboratories Storz Ophthalmics Superpharm Suppositoria Survival Technology Syntex Syosset Labs Tablicaps Tag Pharmaceuticals Takeda Tap Holdings Taro Pharmaceutical Taylor Pharmaceuticals Technilab Theratech Therakos Thames Phamacol Co. Inc. Tican Pharmaceuticals Topiderm Torch Laboratories Torigian Lab UDL Laboratories Unimed UPJ Upjohn USL Upsher-Smith Labs VAL Vale Chemical VAN Vangard VES Vestal VIC Vicks Pharmacy Products VIN Vintage VIR Viratek VIS Vistakon, Inc. VIV Vivan Pharmacal W-A Wyeth Ayerst W-C Warner-Chilcott WAW Warner Wellcome WRR Warrick Pharm WEP WE Pharmaceuticals WEN Wendt Laboratories WPP WES W-W W/L WBY WWT WAL WAR WAT WOC XTT YAM YOS ZCA ZGP West Point Pharma Westwood Squibb Pharmaceuticals West-Ward Wharton Labs Whitby Whiteworth Towne Wallace Labs Warner-Lambert Watson Laboratories Wockhardt Xttrium Laboratories Yamanouchi Yoshitomi Laboratories Zeneca Zenith Goldline Pharmaceuticals MASSACHUSETTS ADDITIONAL LIST OF INTERCHANGEABLE DRUGS AM INOPHYLLINE, EPHEDRINE Hcl Dosage form(s): TABLETS Strength(s): 130mg/25mg M anufacturers: STL Category: OTC AMYL NITRITE Dosage form(s): INHALATION Strength(s): 0.3ml M anufacturers: GLW, CM C Category: PRE-38 ASPIRIN W/ CODEINE PHOSPHATE Dosage form(s): TABLET Strength(s): 325mg/15mg, 30mg, 60mg Manufacturers: BAR, GLW, CHE, GEV, HAL, P/D, ZGP Category: PRE-38 ATROPINE SULFATE Dosage form(s): OPHTHALMIC SOLUTION Strength(s): 0.5%, 1%, 2% OPHTHALMIC OINTMENT 0.5%, 1% Manufacturers: ALC, ALL, ESR, FOU, INV, MUR, B&L, STS, SUR Category: PRE-38 ATROPINE SULFATE COM POUND (ATROPINE SULFATE, SCOPOLAM INE HBr, HYOSCYAM INE SULFATE, PHENOBARBITAL) Dosage form(s): TABLET Strength(s): 0.0194mg/0.0065mg/ 0 1037mg/16.2mg M anufacturers: ALL, CHE, M /P, M AY, TAY, RAH, WES Category: DESI BENZOCAINE, ANTIPYRINE Dosage form(s): OTIC SOLUTION Strength(s): 1.4%, 5.4% Manufacturers: AMB, W-A, CLA, RPC, S-M, THA Category: PRE-38 BENZOYL PEROXIDE Dosage form(s): GELStrength(s): 2.5%, 5%, 10% M anufacturers: BM S, CLA, GAL, STI, SYO, VIC, WES Category: OTC BENZTHIAZIDE Dosage form(s): TABLET Strength(s): 50mg Manufacturers: GEV, PFI, RAH, Category: B BROMPHENIRAMINE MALEATE, DEXTROMETHORPHAN HBr, PSEUDOEPHEDRINE HCl Dosage form(s): SYRUP Strength(s): 2mg/10mg/30mg/5ml M anufacturers: RAH, RPC Category: OTC MASSACHUSETTS ADDITIONAL LIST OF INTERCHANGEABLE DRUGS BROM PHENIRAM INE M ALEATE, PHENYLPROPANOLAMINE HCl, PHENYLEPHRINE, GUAIFENESIN COMBINATION Dosage form(s): SYRUP Strength(s): 4mg/5mg/5mg/100mg/5ml Manufacturers: HAL, LIF, RAH, RPC, Category: OTC CAFFEINE AND SODIUM BENZOATE Dosage form(s): INJECTION Strength(s): 250mg/ml M anufacturers: TAY Category: PRE-38 CALCIUM GLUCONATE Dosage form(s): INJECTION Strength(s): 10% Manufacturers: ARL, APC, APP, CMC, CEN, BAY, ESR, GEN, HYR, KIR, LAN, LIL, M/P, P/D, RIC, STL, P/U , Category: PRE-38 CARBINOXAMINE MALEATE, PSEUDOEPHEDRINE HCl, DEXTROMETHORPHAN HBr Dosage form(s): DROPS Strength(s): 2mg/25mg/4mg/ml SYRUP 4mg/60mg/15mg/5ml M anufacturers: ALP, ROS Category: PRE-38 CHLORAL HYDRATE Dosage form(s): CAPSULE Strength(s): 500mg SYRUP 250mg/5ml, 500mg/5ml M anufacturers: BM S, C/C, ALP, PHC, PUR, ROX, SCE, , ZEN Category: PRE-38 CHLORDIAZEPOXIDE W/ CLIDINIUM BROMIDE Dosage form(s): CAPSULE Strength(s): 5mg/2.5mg Manufacturers: BAR, CHE, EON, GEV, HAL, ROC, LEM, PAR, QUA, ZGP Category: DESI CHLOROTHIAZIDE W/ RESERPINE Dosage form(s): TABLET Strength(s): 250mg/0.125mg, 500mg/0.125mg M anufacturers: M CK, M YL, Category: B CHLORPHENIRAMINE MALEATE Dosage form(s): TABLET Strength(s): 4mg, 8mg, 12mg SYRUP 2mg/5ml M anufacturers: LAN, SCH Category: OTC CHOLINE MAGNESIUM TRISALICYLATE (CHOLINE SALICYLATE, M AGNESIUM SALICYLATE) Dosage form(s): TABLET Strength(s): 500mg (=293mg/362mg), 750mg (=440mg/544mg), 1000mg (=587mg/725mg) M anufacturers: PUF, SID Category: PRE-38 CODEINE PHOSPHATE Dosage form(s): INJECTION Strength(s): 15mg, 30mg, 60mg/ml M anufacturers: ESR, KNO, STL, W-A Category: PRE-38 CODEINE PHOSPHATE /GUAIFENESIN LIQUID Dosage form(s): LIQUID Strength(s): 10mg/100mg/5ml M anufacturers: RAH, HAL Category: PRE-38 CYANOCOBALAMIN Dosage form(s): TABLET Strength(s): 10mcg, 25mcg, CAPSULE 50mcg, 100mcg, 250mcg Manufacturers: APP, BER, BMS, STS, DEL, ESR, INV, LEM, LIL, MMD, MCK, ALP, ORI, P/D, SAV, SOL, P/U, W-A Category: OTC MASSACHUSETTS ADDITIONAL LIST OF INTERCHANGEABLE DRUGS CYCLANDELATE Dosage form(s): Manufacturers: Category: CAPSULE Strength(s): 200mg/400mg CHE, GEV, DAN, FOR, INW, W-A, LAN, LEM, MDP, PAR, PIO, ZGP DESI DEXAMETHASONE Dosage form(s): M anufacturers: Category: TABLET Strength(s):0.25mg, 0.5mg, 0.75mg, 1.5mg, 4mg GEV, DAN, MCK, M YL, ORI, PAR, PRI, RIC, SLV, ROX, , USL B DIETHYLPROPION HCl Dosage form(s): Manufacturers: Category: TABLET Strength(s): 25mg SUSTAINED RELEASE TABLET 75mg CAM, , LEM, MMD, MDP, 3MP B DIETHYLSTILBESTROL Dosage form(s): M anufacturers: Category: TABLET Strength(s): 0.1mg, 0.5mg, 1.5mg VAGINAL SUPPOSITORIES BM S, LIL B DIGOXIN Dosage form(s): M anufacturers: Category: TABLET Strength(s): 0.125mg, 0.25mg, 0.5 mg GLW, AM I PRE-38 DIGOXIN Dosage form(s): M anufacturers: Category: INJECTION Strength(s): 0.25mg/ml, 0.5mg/2ml GLW, ESR, EON, W-A PRE-38 DIMENHYDRINATE Dosage form(s): M anufacturers: Category: TABLET Strength(s): 50mg ANA, STS, CHE, GEV, ESR, LEM , SEA, , W-A OTC DIPHENHYDRAMINE HCl Dosage form(s): M anufacturers: Category: CAPSULE Strength(s): 25mg, 50mg ELIXIR 12.5mg/5ml HAL, ICN, P/D OTC DISULFIRAM Dosage form(s): M anufacturers: Category: TABLET Strength(s): 250mg, 500mg W-A, DAN B EPINEPHRINE HCl Dosage form(s): Manufacturers: Category: INJECTION Strength(s): 0.01%, 0.1% OPHTHALMIC SOLUTION 0.1%, 0.25%, 0.5%, 1%, 2% ABB, ALC, ALL, ARL, ESR,IMS, INV, LAN, P/D, W-A PRE-38 ESTROGENS, ESTERIFIED Dosage form(s): M anufacturers: Category: TABLET Strength(s): 0.3mg, 0.625mg, 1.25mg, 2.5mg BM S, PRI, SLV, SKB, SYN B ETHAVERINE HCl Dosage form(s): M anufacturers: Category: CAPSULE Strength(s): 100mg TABLET BFA, KEN, LEM , M EP PRE-38 ETHINYL ESTRADIOL Dosage form(s): M anufacturers: Category: TABLET Strength(s): 0.02mg, 0.05mg ORI, SCH, P/U B MASSACHUSETTS ADDITIONAL LIST OF INTERCHANGEABLE DRUGS FLUOXYMESTERONE Dosage form(s): TABLET Strength(s): 2mg, 5mg, 10mg M anufacturers: BM S, RPC, P/U Category: B GLYBURIDE Dosage form(s): TABLET Strength(s): 1.25mg, 2.5mg, 5mg M anufacturers: HOE, P/U Category: B HYDRALAZINE HCl, HYDROCHLOROTHIAZIDE, RESERPINE Dosage form(s): TABLET Strength(s): 25mg/15mg/0.1mg M anufacturers: DAN, GEI, LEM Category: B HYDROCHLOROTHIAZIDE W/ RESERPINE Dosage form(s): TABLET Strength(s): 25mg/0.125mg, 50mg/0.125mg, 25mg/0.1mg, 50mg/0.1mg Manufacturers: KNO, CAM, GEI, GEV, DAN, LEM, MCK, PUR, ZGP Category: B HYDROCODONE BITARTRATE W/ PHENYLPROPANOLAMINE Dosage form(s): SYRUP Strength(s): 5mg/25mg/5ml Manufacturers: DPT, ALP, RPC Category: OTHER HYDROCORTISONE, IODOCHLORHYDROXYQUIN Dosage form(s): CREAM Strength(s): 0.5%, 1% / 3% OINTMENT Manufacturers: AMB, ALT, CLA, DER, BAY, DUR, GEI, LEM, ALP, SLV, THA, Category: DESI HYDROFLUMETHIAZIDE, RESERPINE Dosage form(s): TABLET Strength(s): 25mg, 50mg/0.125mg Manufacturers: APO, RPC, ZGP Category: B HYDROQUINONE 4% CREAM Dosage form(s): TOPICAL CREAM Strength(s): 4% M anufacturers: ICN, ETX Category: PRE-62 HYDROQUINONE CREAM 4% Dosage form(s): CREAM Strength(s): 4% M anufacturers: ICN; GLD Category: PRE-1962 HYDROQUINONE 4% CREAM with SUNCREENS Dosage form(s): TOPICAL CREAM Strength(s): 4% M anufacturers: ICN, ETX Category: PRE-62 HYDROQUINONE CREAM 4% with SUNCREEN Dosage form(s): CREAM Strength(s): 4% M anufacturers: ICN; GLD Category: PRE-1962 HYDROQUINONE TOPICAL SOLUTION Dosage form(s): TOPICAL SOLUTION Strength(s): 3% M anufacturers: NEU, GLD Category: PRE-38 8/31/01 105 CMR - 4118.4118 NON-TEXT PAGE 8/31/01 105 CMR - 4118.1 MASSACHUSETTS ADDITIONAL LIST OF INTERCHANGEABLE DRUGS ISOSORBIDE DINITRATE Dosage form(s): SUSTAINED RELEASE CAPSULE Strength(s): 40mg Manufacturers: ASC, GEV, FOR, W-A, SUP Category: B ISOXSUPRINE HCl Dosage form(s): TABLET Strength(s): 10mg, 20mg M anufacturers: GEV, M EA Category: PRE-38 L-HYOSCYAMINE SULFATE Dosage form(s): TABLET Strength(s): 0.125mg M anufacturers: BFA, GLW, SWZ Category: PRE-38 LEVODOPA Dosage form(s): TABLET Strength(s): 250mg, 500mg CAPSULE 100, 250, 500mg M anufacturers: ROC, P&G Category: B MAGNESIUM SALICYLATE Dosage form(s): TABLET Strength(s): 600mg Manufacturers: BFA, END, RBP, MLP, , Category: OTHER MAGNESIUM SULFATE Dosage form(s): INJECTION Strength(s): 10%, 12.5%, 50% M anufacturers: ABB, APP, ARL, CMC, ESR, IMS, LIL Category: PRE-38 MAZINDOL Dosage form(s): TABLET Strength(s): 1mg M anufacturers: SAN, W-A Category: B M EPHOBARBITAL Dosage form(s): TABLET Strength(s): 32mg, 100mg, 200mg M anufacturers: BOW, ICN, S/W Category: PRE-38 METHENAMINE MANDELATE Dosage form(s): SUSPENSION Strength(s): 0.25, 0.5g/5ml TABLET 0.25g, 0.5g, 1g ENTERIC COATED TABLET 0.25g, 0.5g, 1g Manufacturers: GEV, HEA, ALP, P/D, RIC, SLV, TAB Category: PRE-38 M ETHENAM INE COM BINATION (M ETHENAM INE, PHENYLSALICYLATE, ATROPINE SULFATE, HYOSCYAM INE, BENZOIC ACID, M ETHYLENE BLUE) Dosage form(s): TABLET Strength(s): 40.8mg/18mg/0.03mg/ 0.03mg/4.5mg/5.4mg Manufacturers: CHE, LEM, , S-M, STR Category: DESI METHYLENE BLUE Dosage form(s): INJECTION Strength(s): 1% TABLET M anufacturers: ARL, CM C, ESR, TAY, Category: PRE-38 8/16/02 105 CMR - 4119 MASSACHUSETTS ADDITIONAL LIST OF INTERCHANGEABLE DRUGS METHYLTESTOSTERONE Dosage form(s): CAPSULE Strength(s): 10mg SUBL. TABLET 10mg, 25mg Manufacturers: DAN, INW, LAN, PUR, SCH Category: B MORPHINE SULFATE Dosage form(s): SUSTAINED RELEASE TABLET Strength(s): 30mg, 60mg, 100mg M anufacturers: PUF, ROX Category: B NEOSTIGMINE METHYLSULFATE Dosage form(s): INJECTION Strength(s): 1-1000, 1-2000, 1-4000 M anufacturers: CMC, ESR, LAN, S-M, Category: PRE-38 NITROGLYCERIN Dosage form(s): SUBLINGUAL TABLET Strength(s): 0.3mg, 0.4mg, 0.6mg M anufacturers: P/D ETX Category: PRE-38 NORTRIPTYLINE HCl Dosage form(s): CAPSULE Strength(s): 10mg, 25mg M anufacturers: LIL, SAN Category: B NYLIDRIN Dosage form(s): TABLET Strength(s): 6mg, 12mg Manufacturers: GEV, C/P, DAN, ROR, ZGP Category: DESI OPIUM TINCTURE, DEODORIZED Dosage form(s): LIQUID Strength(s): 10% OPIUM M anufacturers: HAL, LIL Category: PRE-38 PAPAVERINE HCl (NON-SUSTAINED RELEASE) Dosage form(s): INJECTION Strength(s): 30mg/ml CAPSULE 75mg, 150mg, 300mg TABLET 30mg, 60mg, 100mg, 150mg, 200mg, 300mg Manufacturers: CHE, CMC, GEV, DAN, HAL, HEA, LAN, LEM, MMD, MYL, PUR, REN, SLV, VAN, EON, ZGP Category: PRE-38 PARALDEHYDE Dosage form(s): LIQUID Strength(s): 100% INJECTION M anufacturers: CM C, ESR, Category: PRE-38 PAREGORIC Dosage form(s): LIQUID Strength(s): 2mg M ORPHINE EQUIV./5ml Manufacturers: APC, BOW, HAL, LAN, LIL, ALP, P/D, PUR, ROX, RPC, STL Category: OTC PENICILLIN G BENZATHINE Dosage form(s): INJECTION Strength(s): 600, 000 UNITS/ml M anufacturers: PFI, W-A Category: B PENTAERYTHRITOL TETRANITRATE Dosage form(s): TABLET Strength(s): 10, 20 SUSTAINED ACTION TABLET 80mg Manufacturers: COO, GEV, DAN, INW, KIR, MER, P/D, PUR, STA, S-M, ZGP Category: DESI 8/16/02 105 CMR - 4120 MASSACHUSETTS ADDITIONAL LIST OF INTERCHANGEABLE DRUGS PHENAZOPYRIDINE HCl Dosage form(s): TABLET Strength(s): 100mg, 200mg Manufacturers: AMI, BAR, COP, C-P, LAN, P/D, QUA, RIC, S-M, TAB, VAN, Category: PRE-38 PHENOBARBITAL Dosage form(s): ELIXIR Strength(s): 20mg/5ml TABLET 15mg, 16mg, 30mg, 32mg, 60mg, 65mg, 100mg Manufacturers: APC, BAR, BOW, GEV, C/P, DAN, HAL, ICN, INW, LAN, LED, LEM, LIL, MMD, ALP, P/D, PUR, REX, ROX, RUG, STL, STA, TAB, EON, W-W, S/W, W-A, ZGP Category: PRE-38 PHENYLEPHRINE HCl Dosage form(s): SOLUTION Strength(s): 0.25%, 1% OPHTHALMIC SOLUTION 0.12, 2.5, 10% M anufacturers: AKO, ALC, ALL, ALP, M UR, B&L, PUF, RPC, STS, S/W Category: PRE-38 PHENYLPROPANOLAMINE HCl, PHENYLEPHRINE HCl, PHENYLTOLOXAMINE CITRATE, CHLORPHENIRAMINE MALEATE Dosage form(s): PEDIATRIC DROPS Strength(s): 5mg/1.25mg/2mg/0.5mg/ml PEDIATRIC SYRUP 5mg/1.25mg/2mg/0.5mg/5ml M anufacturers: ALP, APO Category: PRE-38 PHYTONADIONE Dosage form(s): INJECTION Strength(s): 2mg, 10mg/ml Manufacturers: ABB, ROC, IMS, MCK, SKB Category: B PILOCARPINE HCl Dosage form(s): OPHTHALMIC SOLUTION Strength(s): 0.25%, 0.5%, 1%, 2%, 3%, 4%, 6%, 8% Manufacturers: ALC, CVO, W-A, OPT, B&L, PRO, STS Category: PRE-38 PIPERAZINE CITRATE Dosage form(s): SYRUP Strength(s): 500mg/5ml TABLET 250mg, 500mg M anufacturers: BLU,ALP, GLW, LAN, SLV, S/W Category: PRE-38 POTASSIUM GLUCONATE Dosage form(s): LIQUID Strength(s): 20mEq/15ml Manufacturers: ALP, CMC, GEV, LAN, LED, , RAH, ROX, RPC, S-M, Category: B POTASSIUM IODIDE Dosage form(s): LIQUID Strength(s): SATURATED SOLUTION M anufacturers: ALP, CM C, GEN, GEV, P/R, ROX, RPC, STL, , USL Category: PRE-38 PREDNISOLONE ACETATE Dosage form(s): INJECTION Strength(s): 25, 50, 100mg/ml Manufacturers: ALC, ALL, CTL, STS, LEM, B&L, SCH Category: B PREDNISOLONE TEBUTATE Dosage form(s): INJECTION Strength(s): 20mg/ml Manufacturers: ALP, FOY, RBP, MCK Category: B PROBENECID W/ COLCHICINE Dosage form(s): TABLET Strength(s): 500mg/0.5mg Manufacturers: DAN, LEM, MCK, RIC, ZGP Category: B 8/16/02 105 CMR - 4121 MASSACHUSETTS ADDITIONAL LIST OF INTERCHANGEABLE DRUGS PROMETHAZINE HCl Dosage form(s): TABLET Strength(s): 12.5mg, 25mg, 50mg M anufacturers: ALL, ALT, ALP, DAN, ESR, GEV, KNO, KVN, LEM, LIF, MSM , RPC, S/W, W-A Category: B PROPYLTHIOURACIL Dosage form(s): TABLET Strength(s): 50mg M anufacturers: ANA, KNO, CHE, DAN, LIL, HAL, LAN, LED, P/D, PUR, RIC, TAB, W-W, ZEN Category: B PSEUDOEPHEDRINE HCl Dosage form(s): LIQUID Strength(s): 30mg/5ml TABLET 30mg, 60mg SUSTAINED RELEASE CAPSULE 120mg Manufacturers: ALP, BOW, GLW, CEN, CHE, GEV, DAN, HAL, RBP, LEM, MMD, PAR, ROX, SLV, SUP Category: OTC PSEUDOEPHEDRINE HCl, CHLORPHENIRAMINE MALEATE Dosage form(s): TABLET Strength(s): 60mg/4mg Manufacturers: BER, GLW, ROR, SCH, SKB Category: OTC PSEUDOEPHEDRINE SULFATE, DEXBROMPHENIRAMINE MALEATE Dosage form(s): SUSTAINED RELEASE TABLET Strength(s): 120mg/6mg Manufacturers: COP, GEV, SCH Category: OTC QUININE SULFATE Dosage form(s): TABLET Strength(s): 260mg Manufacturers: CHE, GEV, MMD Category: PRE-38 RAUWOLFIA SERPENTINA Dosage form(s): TABLET Strength(s): 50mg, 100mg Manufacturers: BOW, CMB, GEV, DAN, FER, HAL, ICN, KIR, PAN, PPI, PRI, BMS, SLV, RIC, TAB, VAL, ZEN Category: B RESERPINE Dosage form(s): TABLET Strength(s): 0.1mg, 0.25mg, 0.5mg, 1.0mg INJECTION M anufacturers: BEL, BM S, BOW, CM B, GEV, DAN, FER, GEI, GEN, HAL, ICN, , KIR, LAN, LEM , LIL, M KL, M YL, PAN, PRV, PRI, PUR, SLV, REX, RIC, ROX, STL, TAB, P/U, VAL, ZEN Category: B SALSALATE Dosage form(s): TABLET Strength(s): 500mg, 750mg M anufacturers: GEV, 3M P, SID Category: Pre-38 SODIUM FLUORIDE Dosage form(s): TABLET Strength(s): 0.55mg, 1.1mg, 2.2mg (NaF) DROPS 0.125mg (F-)/DROP CHEWABLE TABLET 0.55mg, 1.1mg, 2.2mg (NaF) M anufacturers: ABL, KNO, BOW, CHE, CM C, COP, C-P, GEN, HOY, KIR, RIC, RUG, STL, Category: PRE-38 SULFAMETHOXAZOLE, PHENAZOPYRIDINE HCl Dosage form(s): TABLET Strength(s): 500/100mg M anufacturers: COP, RIC Category: DESI SULFASALAZINE Dosage form(s): ENTERIC COATED TABLETS Strength(s): 500mg M anufacturers: DAN, LED, LEM, MUT, KBP, ROW, SUP, VIP Category: B 8/16/02 105 CMR - 4122 MASSACHUSETTS ADDITIONAL LIST OF INTERCHANGEABLE DRUGS SULFISOXAZOLE PHENAZOPYRIDINE HCl Dosage form(s): TABLET Strength(s): 500/50mg Manufacturers: COP, KAY, ROC, ROX, SLV, S-M, STN, VAN, Category: DESI TERBUTALINE SULFATE Dosage form(s): TABLET Strength(s): 2.5mg, 5mg M anufacturers: GEI, M M D Category: B TESTOSTERONE Dosage form(s): INJECTION Strength(s): 25mg/ml, 50mg/ml, 100mg/ml Manufacturers: BAT, STS,RBP, LIL, MAY Category: PRE-38 TETRACAINE HCl Dosage form(s): OPHTHALMIC SOLUTION Strength(s): 0.5% M anufacturers: ALC, GEN, B&L, S-M , S/W Category: PRE-38 THEOPHYLLINE (NON-SUSTAINED RELEASE) Dosage form(s): CAPSULE Strength(s): 100mg, 200mg TABLET 100, 125, 200, 225, 250mg Manufacturers: ALP, BEL, BER, CNC, CTL, FER, HAL, KNO, LAN, LIF, MMD, PAN, P/A, RIC, 3MP, ROR, ROX, RPC, SEA, Category: B THEOPHYLLINE, GUAIFENESIN Dosage form(s): ELIXIR Strength(s): 150mg/90mg/15ml LIQUID M anufacturers: M EA, RPC Category: PRE-38 THEOPHYLLINE, POTASSIUM IODIDE (THEOPHYLLINE, POTASSIUM IODIDE, ALCOHOL) Dosage form(s): ELIXIR Strength(s): 80mg/130mg/10%/15ml Manufacturers: FOR, ALP, RPC Category: PRE-38 THYROGLOBULIN Dosage form(s): TABLET Strength(s): 65mg M anufacturers: RIC, P/D, W-L Category: B TRIAMCINOLONE DIACETATE Dosage form(s): INJECTION Strength(s): 25mg, 40mg/ml M anufacturers: BM S, LED, LEM , STS Category: B TRICHLORMETHIAZIDE, RESERPINE Dosage form(s): TABLET Strength(s): 4mg/0.1mg M anufacturers: M M D, SCH Category: B TRIPROLIDINE HCl, PSEUDOEPHEDRINE HCl Dosage form(s): TABLET Strength(s): 2.5mg/60mg SYRUP 1.25mg/30mg/5ml Manufacturers: GLW, ALP, CHE, CNC, GEV, HAL, ICN, LED, LEM, LIF, NEW, B&L, PRI, PUR, ROX, SLV, SUP, VAN, ZEN Category: OTC TRYPSIN, BALSAM PERU, CASTOR OIL Dosage form(s): TOPICAL AEROSOL Strength(s): 0.1mg/72.5mg/650mg IN EACH 0.82CC SPRAY M anufacturers: COP, HIC Category: PRE-38 8/16/02 105 CMR - 4123 720.200: continued PARTIAL PROPRIETARY BRAND CROSS-REFERENCE Generically equivalent drug products in the same strength and dosage form listed in the Additional List are interchangeable if their respective manufacturers are listed for that product. This partial cross- reference section does not attempt to list all brand names which are approvedforinterchange.Formost products only one, usually the innovator or most commonly prescribed brand, is listed below for quick reference purposes. See page 4105 for precise instructions for determining the interchangeability of drug products. BRAND SEE (ATROPINE SULFATE, HYOSCINE HBr, HYOSCYAMINE HBr, PHENOBARBITAL) (THEOPHYLLINE, POTASSIUM IODIDE, ALCOHOL) ACTIFED . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . TRIPROLIDINE HCl, PSEUDOEPHEDRINE HCl ANDROID . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . METHYLTESTOSTERONE ANTABUSE DISULFIRAM AQUAMEPHYTON . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . PHYTONADIONE AURALGAN . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . BENZOCAINE, ANTIPYRINE AZO-GANTANOL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . SULFAMETHOXAZOLE, PHENAZOPYRIDINE AZO-GANTRISIN . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . SULFISOXAZOLE PHENAZOPYRIDINE HCl AZULFADINE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . SULFASALAZINE BENADRYL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . DIPHENHYDRAMINE HCl CYANOCOBALAMIN BICILLIN . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . PENICILLIN G BENZATHINE BRETHINE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . TERBUTALINE SULFATE CHLOR-TRIMETON . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . CHLORPHENIRAMINE MALEATE COL-BENEMID . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . PROBENECID W/ COLCHICINE CYCLANDELATE DECADRON . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . DEXAMETHASONE DESQUAM . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . BENZOYL PEROXIDE DIMETANE DX . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . BROMPHENIRAMINE, DEXTROMETHORPHAN, PSEUDOEPHEDRINE DIUPRESS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . CHLOROTHIAZIDE W/ RESERPINE DONNATAL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ATROPINE SULFATE COMPOUND DRAMAMINE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . DIMENHYDRINATE DRIXORAL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . (product reformulated) ECONOPRED . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . PREDNISOLONE ACETATE ELIXOPHYLLINE KI . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . THEOPHYLLINE, POTASSIUM IODIDE EMPIRIN W/ CODEINE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ASPIRIN W/ CODEINE PHOSPHATE ESTINYL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ETHINYL ESTRADIOL EXNA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . BENZTHIAZIDE FEDAHIST . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . PSEUDOEPHEDRINE HCl, CHLORPHENIRAMINE MALEATE GLAUCON . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . EPINEPHRINE HCl GRANULEX . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . TRYPSIN, BALSAM PERU, CASTOR OIL HALOTESTIN . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . FLUOX\YMESTERONE HYCOMINE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . HYDROCODONE BITARTRATE W/ PHENYLPROPANOLAMINE HYDROPRES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . HYDROCHLOROTHIAZIDE W/ RESERPINE ISOPTO CARPINE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . PILOCARPINE HCl ISORDIL TEMBID . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ISOSORBIDE DINITRATE ISUPREL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ISOPROTERENOL HCl KAON . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . POTASSIUM GLUCONATE KENALOG . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . TRIAMCINOLONE DIACETATE LARODOPA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . LEVODOPA LEVSIN . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . L-HYOSCYAMINE SULFATE LIBRAX . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . CHLORDIAZEPOXIDE W/CLIDINIUM BROMIDE MANDELAMINE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . METHENAMINE MANDELATE MEBARAL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . MEPHOBARBITAL MENEST . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ESTROGENS, ESTERIFIED METALONE T.B.A . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . PREDNISOLONE TEBUTATE MICRONASE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . GLYBURIDE MAGNESIUM SALICYLATE NEO-SYNEPHRINE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . PHENYLEPHRINE HCl 8/16/02 105 CMR - 4124 720.200: continued BRAND SEE CHLORAL HYDRATE PAMELOR . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . NORTRIPTYLINE HCl PHENERGAN PLAIN . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . PROMETHAZINE HCl PONTOCAINE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . TETRACAINE HCl PROSED . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . METHENAMINE COMBINATION (METHENAMINE, PHENYLSALICYLATE, ATROPINE SULFATE, HYOSCYAMINE, BENZOIC ACID METHYLENE BLUE) PROSTIGMINE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . NEOSTIGMINE METHYLSULFATE PYRIDIUM . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . PHENAZOPYRIDINE HCl QUINAMM . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . QUININE SULFATE SALUTENSIN . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . HYDROFLUMETHIAZIDE, RESERPINE SANOREX . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . MAZINDOL SERAPES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . HYDRALAZINE HCl, HYDROCHLOROTHIAZIDE, RESERPINE SLO-PHYLLIN GG . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . THEOPHYLLINE, GUAIFENESIN SLO-PHYLLIN . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . THEOPHYLLINE (NON-SUSTAINED RELEASE) SSKI . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . POTASSIUM IODIDE SUDAFED . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . PSEUDOEPHEDRINE HCl SYNTHROID . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . LEVOTHYROXINE SODIUM TENUATE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . DIETHYLPROPION HCl TESTOSTERONE TUINAL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . AMOBARBITAL SODIUM, SECOBARBITAL SODIUM VASODILAN . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ISOXSUPRINE 8/16/02 105 CMR - 4125 (PAGES 4127 THROUGH 4132 ARE RESERVED FOR FUTURE USE.) 8/16/02 105 CMR - 4126