TABLE OF CHRONIC HRVs

The heading for each item contains the chemical name and, in parenthesis, the CAS RN. Each item lists the chronic HRV, the equation used to develop the chronic HRV, and the variables necessary for the equation. The equations used to develop the chronic HRV are designated as follows: "A" means calculating the NOAEL [HEC] or LOAEL [HEC] or BMC [HEC] under part 4717.8300 , subpart 3, and applying the general equation under part 4717.8300 , subpart 2; "B" means calculating the NOAEL [HEC] or LOAEL [HEC] or BMC [HEC] under part 4717.8300 , subpart 4, and applying the general equation under part 4717.8300 , subpart 2; "C" means calculating the NOAEL [HEC] or LOAEL [HEC] or BMC [HEC] under part 4717.8300 , subpart 5, and applying the general equation under part 4717.8300 , subpart 2; "D" means calculating the NOAEL [HEC] or LOAEL [HEC] or BMC [HEC] under part 4717.8300 , subpart 6, and applying the general equation under part 4717.8300 , subpart 2; and "E" means applying the equation under part 4717.8400 , subpart 2. The endpoint of concern is listed for use in determining a cancer index under part 4717.8550 or a hazard index under part 4717.8600 . The unit risk for carcinogens is expressed as risk per (µg/m 3 ). TABLE OF CHRONIC HRVs A. Acetaldehyde (75-07-0) Chronic HRV (µg/m 3 ) 5 Endpoint of concern Cancer Equation E Unit risk 2.2E-6 B. Acetonitrile (75-05-8) Chronic HRV (µg/m 3 ) 60 Endpoint of concern Mortality Equation D NOAEL [HEC] (mg/m 3 ) 6E1 Uncertainty factor 1,000 C. Acrylonitrile (107-13-1) Chronic HRV (µg/m 3 ) 0.1 Endpoint of concern Cancer Equation E Unit risk 6.8E-5 D. Ammonia (7664-41-7) Chronic HRV (µg/m 3 ) 80 Endpoint of concern Upper and lower respiratory system Equation C NOAEL [HEC] (mg/m 3 ) 2.3 Uncertainty factor 30 E. Antimony trioxide (1309-64-4) Chronic HRV (µg/m 3 ) 0.2 Endpoint of concern Lower respiratory system Equation A BMC [HEC] (mg/m 3 ) 7.4E-2 Uncertainty factor 300 F. Arsenic (7440-38-2) Chronic HRV (µg/m 3 ) 0.002 Endpoint of concern Cancer Equation E Unit risk 4.3E-3 G. Benzene (71-43-2) Chronic HRV (µg/m 3 ) 1.3 - 4.5 Endpoint of concern Cancer Equation E Unit risk 2.2E-6 to 7.8E-6 H. Benzidine (92-87-5) Chronic HRV (µg/m 3 ) 0.0002 Endpoint of concern Cancer Equation E Unit risk 6.7E-2 I. Beryllium (7440-41-7) Chronic HRV (µg/m 3 ) 0.004 Endpoint of concern Cancer Equation E Unit risk 2.4E-3 J. Bis(chloromethyl)ether (542-88-1) Chronic HRV (µg/m 3 ) 0.0002 Endpoint of concern Cancer Equation E Unit risk 6.2E-2 K. Bromomethane (74-83-9) Chronic HRV (µg/m 3 ) 5 Endpoint of concern Upper respiratory system Equation C LOAEL [HEC] (mg/m 3 ) 4.8E-1 Uncertainty factor 100 L. 1,3-Butadiene (106-99-0) Chronic HRV (µg/m 3 ) 0.04 Endpoint of concern Cancer Equation E Unit risk 2.8E-4 M. Cadmium (7440-43-9) Chronic HRV (µg/m 3 ) 0.006 Endpoint of concern Cancer Equation E Unit risk 1.8E-3 N. Carbon disulfide (75-15-0) Chronic HRV (µg/m 3 ) 700 Endpoint of concern Nervous system Equation D BMC [HEC] (mg/m 3 ) 1.97E1 Uncertainty factor 30 O. 2-Chloroacetophenone (532-27-4) Chronic HRV (µg/m 3 ) 0.03 Endpoint of concern Upper and lower respiratory system Equation C LOAEL [HEC] (mg/m 3 ) 3E-2 Uncertainty factor 1,000 P. Chromium VI (18540-29-9) Chronic HRV (µg/m 3 ) 0.0008 Endpoint of concern Cancer Equation E Unit risk 1.2E-2 Q. Coke oven emissions (8007-45-2) Chronic HRV (µg/m 3 ) 0.02 Endpoint of concern Cancer Equation E Unit risk 6.2E-4 R. 1,2-Dibromoethane (106-93-4) Chronic HRV (µg/m 3 ) 0.05 Endpoint of concern Cancer Equation E Unit risk 2.2E-4 S. Dichloromethane (75-09-2) Chronic HRV (µg/m 3 ) 20 Endpoint of concern Cancer Equation E Unit risk 4.7E-7 T. 1,3-Dichloropropene (542-75-6) Chronic HRV (µg/m 3 ) 20 Endpoint of concern Upper respiratory system BMC [HEC] (mg/m 3 ) 7.2E-1 Equation C Uncertainty factor 30 U. Dichlorvos (62-73-7) Chronic HRV (µg/m 3 ) 0.5 Endpoint of concern Nervous system Equation D NOAEL [HEC] (mg/m 3 ) 5E-2 Uncertainty factor 100 V. Diesel particulates (*) Chronic HRV (µg/m 3 ) 5 Endpoint of concern Lower respiratory system Equation A NOAEL [HEC] (mg/m 3 ) 1.55E-1 Uncertainty factor 30 W. N,N-dimethylformamide (68-12-2) Chronic HRV (µg/m 3 ) 30 Endpoint of concern Gastrointestinal system and hepatic system Equation D LOAEL [HEC] (mg/m 3 ) 7.9 Uncertainty factor 300 X. Epichlorohydrin (106-89-8) Chronic HRV (µg/m 3 ) 8 Endpoint of concern Cancer Equation E Unit risk 1.2E-6 Y. 1,2-Epoxybutane (106-88-7) Chronic HRV (µg/m 3 ) 20 Endpoint of concern Upper respiratory system Equation C LOAEL [HEC] (mg/m 3 ) 4.8 Uncertainty factor 300 Z. Ethylene glycol monobutyl ether (111-76-2) Chronic HRV (µg/m 3 ) 13,000 Endpoint of concern Hematologic system Equation D BMC [HEC] (mg/m 3 ) 3.8E2 Uncertainty factor 30 AA. Formaldehyde (50-00-0) Chronic HRV (µg/m 3 ) 0.8** Endpoint of concern Cancer Equation E Unit risk 1.3E-5 BB. 1,6-Hexamethylene diisocyanate (822-06-0) Chronic HRV (µg/m 3 ) 0.01** Endpoint of concern Upper and lower respiratory system Equation C NOAEL [HEC] (mg/m 3 ) 1E-3 Uncertainty factor 100 CC. n-Hexane (110-54-3) Chronic HRV (µg/m 3 ) 2,000 Endpoint of concern Nervous system and upper respiratory system Equation D LOAEL [HEC] (mg/m 3 ) 7.3E1 Uncertainty factor 30 DD. Hydrazine/Hydrazine sulfate (302-01-2) Chronic HRV (µg/m 3 ) 0.002 Endpoint of concern Cancer Equation E Unit risk 4.9E-3 EE. Hydrogen chloride (7647-01-0) Chronic HRV (µg/m 3 ) 20 Endpoint of concern Upper respiratory system Equation C LOAEL [HEC] (mg/m 3 ) 6.1 Uncertainty factor 300 FF. Hydrogen cyanide (74-90-8) Chronic HRV (µg/m 3 ) 3 Endpoint of concern Endocrine system and nervous system Equation D LOAEL [HEC] (mg/m 3 ) 2.5 Uncertainty factor 1,000 GG. Manganese (7439-96-5) Chronic HRV (µg/m 3 ) 0.2 Endpoint of concern Nervous system Equation B BMC [HEC] (mg/m 3 ) 1.9E-2 Uncertainty factor 100 HH. Methyl methacrylate (80-62-6) Chronic HRV (µg/m 3 ) 700** Endpoint of concern Upper and lower respiratory system Equation C BMC [HEC] (mg/m 3 ) 7.2 Uncertainty factor 10 II. Methylene diphenyl diisocyanate (MDI) and polymeric MDI (101-68-8 and 9016-87-9) Chronic HRV (µg/m 3 ) 0.6** Endpoint of concern Upper and lower respiratory system Equation A BMC [HEC] (mg/m 3 ) 6E-2 Uncertainty factor 100 JJ. Nickel refinery dust (*) Chronic HRV (µg/m 3 ) 0.04 Endpoint of concern Cancer Equation E Unit risk 2.4E-4 KK. Nickel subsulfide (12035-72-2) Chronic HRV (µg/m 3 ) 0.02 Endpoint of concern Cancer Equation E Unit risk 4.8E-4 LL. 2-Nitropropane (79-46-9) Chronic HRV (µg/m 3 ) 20 Endpoint of concern Hepatic system Equation D LOAEL [HEC] (mg/m 3 ) 1.6E1 Uncertainty factor 1,000 MM. Propylene oxide (75-56-9) Chronic HRV (µg/m 3 ) 3 Endpoint of concern Cancer Equation E Unit risk 3.7E-6 NN. Styrene (100-42-5) Chronic HRV (µg/m 3 ) 1000 Endpoint of concern Nervous system Equation D NOAEL [HEC] (mg/m 3 ) 3.4E1 Uncertainty factor 30 OO. Toluene (108-88-3) Chronic HRV (µg/m 3 ) 400 Endpoint of concern Nervous system and upper respiratory system Equation D LOAEL [HEC] (mg/m 3 ) 1.19E2 Uncertainty factor 300 PP. 2,4-/2,6-Toluene diisocyanate (26471-62-5) Chronic HRV (µg/m 3 ) 0.08** Endpoint of concern Lower respiratory system Equation D NOAEL [HEC] (mg/m 3 ) 2.3E-3 Uncertainty factor 30 QQ. Vinyl acetate (108-05-4) Chronic HRV (µg/m 3 ) 200 Endpoint of concern Upper respiratory system Equation C NOAEL [HEC] (mg/m 3 ) 5 Uncertainty factor 30 RR. Vinyl chloride (75-01-4) Chronic HRV (µg/m 3 ) 1 Endpoint of concern Cancer Equation E Unit risk 8.8E-6 * This HRV is for a chemical mixture which, therefore, does not have a chemical-specific number assigned by the Chemical Abstracts Service. ** This HRV may not provide protection for individuals who have been previously sensitized to this chemical.