Minn. R. 4717.8200
TABLE OF ACUTE HRVs
The heading for each item contains the chemical name and, in parenthesis, the CAS RN. Each item lists the acute HRV, the equation used to develop the acute HRV, and the variables necessary for the equation. The equations used to develop the acute HRV are designated as follows: "A" means calculating the NOAEL or LOAEL or BMC [ADJ] under part 4717.8500 , subpart 3, and applying the general equation under part 4717.8500 , subpart 2; "B" means calculating the NOAEL [ADJ] or LOAEL [ADJ] or BMC [ADJ] under part 4717.8500 , subpart 4, and applying the general equation under part 4717.8500 , subpart 2; "C" means calculating the BMC or BMC [ADJ] under part 4717.8500 ; and "D" means applying the equation under part 4717.8500 , subpart 5. The endpoint of concern is listed for use in determining a hazard index under part 4717.8600 . TABLE OF ACUTE HRVs A. Ammonia (7664-41-7) Acute HRV (µg/m 3 ) 3,200 Endpoint of concern Irritant - eye, respiratory system Equation C BMC (mg/m 3 ) 9.5 Uncertainty factor 3 B. Arsine (7784-42-1) Acute HRV (µg/m 3 ) 200 Endpoint of concern Hematologic* Equation A NOAEL [ADJ] (mg/m 3 ) 1.6E1 Uncertainty factor 100 C. Benzene (71-43-2) Acute HRV (µg/m 3 ) 1,000 Endpoint of concern Reproductive/developmental Equation D NOAEL (mg/m 3 ) 1.3E2 Uncertainty factor 100 D. Carbon disulfide (75-15-0) Acute HRV (µg/m 3 ) 6,000 Endpoint of concern Reproductive/developmental Equation D NOAEL (mg/m 3 ) 6.2E2 Uncertainty factor 100 E. Chlorine (7882-50-5) Acute HRV (µg/m 3 ) 290 Endpoint of concern Irritant - respiratory system Equation A NOAEL (mg/m 3 ) 2.9 Uncertainty factor 10 F. Chloroform (67-66-3) Acute HRV (µg/m 3 ) 150 Endpoint of concern Reproductive/developmental Equation D LOAEL (mg/m 3 ) 1.5E2 Uncertainty factor 1,000 G. Dichloromethane (75-09-2) Acute HRV (µg/m 3 ) 10,000 Endpoint of concern Nervous system Equation A NOAEL [ADJ] (mg/m 3 ) 6.8E2 Uncertainty factor 60 H. 1,4-Dioxane (123-91-1) Acute HRV (µg/m 3 ) 3,000 Endpoint of concern Irritant - eye and nasal Equation A LOAEL [ADJ] (mg/m 3 ) 1.8E2 Uncertainty factor 60 I. Ethyl benzene (100-41-4) Acute HRV (µg/m 3 ) 10,000 Endpoint of concern Reproductive/developmental Equation D NOAEL (mg/m 3 ) 4.3E2 Uncertainty factor 30 J. Ethyl chloride (75-00-3) Acute HRV (µg/m 3 ) 100,000 Endpoint of concern Reproductive/developmental Equation D NOAEL (mg/m 3 ) 4E3 Uncertainty factor 30 K. Ethylene glycol monoethyl ether (110-80-5) Acute HRV (µg/m 3 ) 400 Endpoint of concern Reproductive/developmental Equation D NOAEL (mg/m 3 ) 3.7E1 Uncertainty factor 100 L. Ethylene glycol monoethyl ether acetate (111-15-9) Acute HRV (µg/m 3 ) 100 Endpoint of concern Reproductive/developmental Equation D LOAEL (mg/m 3 ) 1.4E2 Uncertainty factor 1,000 M. Ethylene glycol monomethyl ether (EGME) (109-86-4) or 2-methoxyethanol Acute HRV (µg/m 3 ) 90 Endpoint of concern Reproductive/developmental Equation D NOAEL (mg/m 3 ) 9.3 Uncertainty factor 100 N. Formaldehyde (50-00-0) Acute HRV (µg/m 3 ) 94 Endpoint of concern Irritant - eye and respiratory system Equation C BMC (mg/m 3 ) 9.4E-1 Uncertainty factor 10 O. Hydrogen chloride (7647-01-1) Acute HRV (µg/m 3 ) 2,700 Endpoint of concern Irritant - eye and respiratory system Equation A NOAEL (mg/m 3 ) 2.7 Uncertainty factor 1 P. Hydrogen cyanide (74-90-8) Acute HRV (µg/m 3 ) 700 Endpoint of concern Nervous system* Equation A NOAEL (mg/m 3 ) 6.8E1 Uncertainty factor 100 Q. Hydrogen fluoride (7664-39-3) Acute HRV (µg/m 3 ) 240 Endpoint of concern Irritant - respiratory system Equation A NOAEL [ADJ] (mg/m 3 ) 2.4 Uncertainty factor 10 R. Methanol (67-56-1) Acute HRV (µg/m 3 ) 25,000 Endpoint of concern Nervous system Equation A NOAEL [ADJ] (mg/m 3 ) 2.5E2 Uncertainty factor 10 S. Methyl bromide (74-83-9) Acute HRV (µg/m 3 ) 2,000 Endpoint of concern Nervous system* Equation A LOAEL [ADJ] (mg/m 3 ) 1.4E2 Uncertainty factor 60 T. Methyl ethyl ketone (78-93-3) Acute HRV (µg/m 3 ) 10,000 Endpoint of concern Irritant - eye and respiratory system Equation A LOAEL [ADJ] (mg/m 3 ) 8E2 Uncertainty factor 60 U. Nickel and nickel compounds (**) Acute HRV (µg/m 3 ) 11 Endpoint of concern Irritant - respiratory system Equation A LOAEL (mg/m 3 ) 6.7E-2 Uncertainty factor 6 V. Nitric acid (7697-37-2) Acute HRV (µg/m 3 ) 130 Endpoint of concern Irritant - respiratory system Equation A NOAEL (mg/m 3 ) 1.29E-1 Uncertainty factor 1 W. Phenol (108-95-2) Acute HRV (µg/m 3 ) 5,800 Endpoint of concern Irritant - eye and respiratory system Equation B NOAEL [ADJ] (mg/m 3 ) 5.8E1 Uncertainty factor 10 X. Phosgene (75-44-5) Acute HRV (µg/m 3 ) 4 Endpoint of concern Irritant - respiratory system* Equation A NOAEL [ADJ] (mg/m 3 ) 4E-1 Uncertainty factor 100 Y. Sodium hydroxide (1310-93-2) Acute HRV (µg/m 3 ) 8 Endpoint of concern Irritant - eye, skin, and respiratory system Equation A LOAEL [ADJ] (mg/m 3 ) 5E-1 Uncertainty factor 60 Z. Styrene (100-42-5) Acute HRV (µg/m 3 ) 21,000 Endpoint of concern Irritant - eye and respiratory system Equation A NOAEL [ADJ] (mg/m 3 ) 2.1E2 Uncertainty factor 10 AA. Tetrachloroethylene or perchlorethylene (127-18-4) Acute HRV (µg/m 3 ) 20,000 Endpoint of concern Irritant - eye and respiratory and nervous systems Equation B LOAEL [ADJ] (mg/m 3 ) 1.2E3 Uncertainty factor 60 BB. Toluene (108-88-3) Acute HRV (µg/m 3 ) 37,000 Endpoint of concern Irritant - eye and respiratory and nervous systems Equation B NOAEL [ADJ] (mg/m 3 ) 3.7E2 Uncertainty factor 10 CC. 1,1,1-Trichloroethane or methyl chloroform (71-55-6) Acute HRV (µg/m 3 ) 140,000 Endpoint of concern Nervous system Equation A NOAEL (mg/m 3 ) 1.37E3 Uncertainty factor 10 DD. Trichloroethylene (79-01-6) Acute HRV (µg/m 3 ) 2,000 Endpoint of concern Reproductive/developmental Equation D LOAEL (mg/m 3 ) 5.4E2 Uncertainty factor 300 EE. Triethylamine (121-44-8) Acute HRV (µg/m 3 ) 2,800 Endpoint of concern Irritant - eye; transient corneal edema Equation B NOAEL [ADJ] (mg/m 3 ) 2.8E1 Uncertainty factor 10 FF. Vanadium pentoxide (1314-62-1) Acute HRV (µg/m 3 ) 30 Endpoint of concern Irritant - respiratory system Equation B LOAEL [ADJ] (mg/m 3 ) 3E-1 Uncertainty factor 10 GG. Xylenes (1330-20-7) Acute HRV (µg/m 3 ) 43,000 Endpoint of concern Irritant - eye and respiratory and nervous systems Equation A NOAEL (mg/m 3 ) 4.3E2 Uncertainty factor 10 * This HRV is for a chemical where there is little magnitude difference between the level where mild irritancy occurs and levels where more severe adverse health effects occur. ** This HRV is for a chemical mixture which, therefore, does not have a chemical-specific number assigned by the Chemical Abstracts Service.