15 MAC Pt. 2, Ch. 1, R. 1.20.3
Time of Reporting – Timeliness of reporting shall be as directed by existing CMS
Cite as 15 Miss. Admin. Code Pt. 2, Ch. 1, R. 1.20.3
Time of Reporting – Timeliness of reporting shall be as directed by existing CMS
/NHSN reporting requirements.
Source: Miss.Code Ann. §41-3-17
Appendices to the Rules and Regulations
Governing Reportable Diseases and Conditions
Appendix A
List of Reportable Diseases and Conditions
Appendix A. List of officially reportable diseases and conditions
The following diseases or conditions are hereby declared to be reportable.
Class 1A:
Diseases of major public health importance which shall be reported directly to the
Department of Health by telephone within 24 hours of first knowledge or
suspicion. Class 1A diseases and conditions are dictated by requiring an
immediate public health response. Laboratory directors have an obligation to
report laboratory findings for selected diseases (Refer to Appendix B).
Any Suspected Outbreak (including foodborne and waterborne outbreaks)
(Possible biological weapon agents appear in bold italics)
Anthrax
Pertussis
Botulism (includes foodborne, infant or wound)
Plague
Escherichia coli O157:H7 and any shiga
Poliomyelitis
toxin-producing E. coli (STEC)
Rabies (human or animal)
Glanders
Ricin intoxication (castor beans)
Haemophilus influenzae Invasive Disease†‡
Smallpox
Hemolytic Uremic Syndrome-
Tuberculosis
post-diarrheal (HUS)
Viral hemorrhagic fevers (filoviruses
Hepatitis A
[e.g., Ebola, Marburg] and arena
Measles
viruses [e.g., Lassa, Machupo])
Neisseria meningitidis Invasive Disease†‡
Any unusual disease or manifestation of illness, including but not limited to the appearance
of a novel or previously controlled or eradicated infectious agent, or biological or chemical
toxin.
†Usually presents as meningitis or septicemia, or less commonly as cellulitis, epiglottitis,
osteomyelitis, pericarditis or septic arthritis.
‡Specimen obtained from a normally sterile site.
Class 1B: Diseases of major public health importance which shall be reported directly to the
Department of Health by telephone on the next business day after first knowledge
or suspicion. Class 1B diseases and conditions require individual case
investigation, but not an immediate public health response. Laboratory directors
have an obligation to report laboratory findings for selected diseases (Refer to
Appendix B in the Rules and Regulations Governing Reportable Diseases and
Conditions)
Arboviral infections
Respiratory Syncytial Virus (RSV)-
Chikungunya virus,
Associated Pediatric Mortality
Eastern Equine Encephalitis virus,
(<18 years of age)
Zika virus (including Congenital Zika virus
SARS-CoV-2 Associated Mortality in
Infection and Congenital Zika Syndrome)
Pregnancy
Class 2:
Diseases or conditions of public health importance of which individual cases shall
be reported by mail, telephone or electronically, within 1 week of diagnosis. In
outbreaks or other unusual circumstances they shall be reported the same as Class
1A. Class 2 diseases and conditions are those for which an immediate public
health response is not needed for individual cases.
Anaplasmosis
Lyme disease
Arboviral infection including but not limited to
Malaria
California group,
Meningitis other than Meningococcal or
Dengue,
Haemophilus influenzae
LaCrosse virus,
Mumps
St. Louis encephalitis virus,
M. tuberculosis Infection (positive TST
West Nile virus
or positive IGRA*)
Western Equine Encephalitis virus
Poisonings**(including elevated blood
Chlamydia trachomatis, genital infection
lead levels***)
Creutzfeldt-Jakob Disease, including new variant
Rocky Mountain spotted fever
Ehrlichiosis
Rubella (including congenital)
Enterococcus, invasive infection‡, vancomycin
Spinal Cord Injuries
resistant
Streptococcus pneumoniae, invasive
Gonorrhea
infection‡
Hepatitis (acute, viral only)
Tetanus
Note-Hepatitis A requires Class 1A Report
Trichinosis
Hepatitis B infection in pregnancy
Typhus Fever
HIV Infection in pregnancy
Viral Encephalitis in horses and
Listeriosis
ratities****
‡Specimen obtained from a normally sterile site.
*TST-tuberculin skin test; IGRA-Interferon-Gamma Release Assay (to include size of TST in
millimeters and numerical results of IGRA testing).
Brucellosis
SARS-CoV-2 Associated Multisystem
Chancroid
Inflammatory Syndrome in Children
Cholera
(MIS-C) <21 years of age
Diphtheria
SARS-CoV-2 Associated Pediatric
Encephalitis (human)
Mortality (<18 years of age)
HIV infection-including AIDS
Staphylococcus aureus,
Influenza-Associated Pediatric Mortality
vancomycin resistant (VRSA) or
(<18 years of age)
vancomycin intermediate (VISA)
Legionellosis
Syphilis (including congenital)
Melioidosis
Tularemia
Non-cholera Vibrio disease
Typhoid Fever
Psittacosis
Varicella infection, Primary, in
Q Fever
>15 years of age
Yellow Fever
**Reports for poisonings shall be made to Mississippi Poison Control Center, UMMC 1-800-
222-1222
***Elevated Blood Levels should be reported to the MSDH Lead Program at 601-576-7447.
Blood lead levels (venous) ≥3.5µg/dL in patients less than or equal to 6 years of age.
****Except for rabies, and equine encephalitis, diseases occurring in animals are not required to
be reported to the MSDH.
Class 3:
Laboratory based surveillance. To be reported by laboratory only. Diseases or
conditions of public health importance of which individual laboratory findings
shall be reported by mail, telephone, or electronically within one week of
completion of laboratory test (refer to Appendix B).
All blood lead test results in patients ≤6 years of
CD4 count and HIV Viral Load*
age
Chagas Disease (American trypanosomiasis)
Campylobacteriosis
Cryptosporidiosis
Candida auris
Hansen Disease (Leprosy)
Carbapenem-resistant Acinetobacter
Hepatitis C infection
baumannii (CRAB)
Hepatitis C RNA results**
Carbapenem-resistant Enterobacteriaceae (CRE)
Nontuberculous Mycobacterial Disease
Carbapenem-resistant Pseudomonas aeruginosa
Salmonellosis
(CRPA)
Shigellosis
*HIV associated CD4 (T4) lymphocyte results of any value and HIV viral load results, both
detectable and undetectable
**All positive AND negative Hepatitis C RNA results
Class 4:
Diseases of public health importance for which immediate reporting is not
necessary for surveillance or control efforts. Diseases and conditions in this
category shall be reported to the Mississippi Cancer Registry within six months of
the date of first contact for the reportable condition.
The National Program of Cancer Registries at the Centers for Disease Control and
Prevention requires the collection of certain diseases and conditions. A
comprehensive reportable list including ICD9CM/ICD10CM codes is available on
the Mississippi Cancer Registry website,
https://www.umc.edu/cancerinstitute/Cancer-Research/Cancer-
Registries/Mississippi%20Cancer%20Registry/Resources1/Overview.html.
Each record shall provide a minimum set of data items which meets the uniform
standards required by the National Program of Cancer Registries and documented
in the North American Association of Central Cancer Registries (NAACCR)
Appendix B
Laboratory Results That Must be
Reported to the Mississippi State Department of Health
Laboratory Results That Must be
Reported to the Mississippi State Department of Health
Laboratories shall report these findings to the Mississippi State Department of Health at least WEEKLY. Diseases in
bold type Are Class 1A disease and shall be reported immediately by telephone. Isolates of organisms marked with
a dagger (†) shall be sent to the Mississippi State Department of Health Public Health Laboratory. All referring
laboratories should call the Public Health Laboratory at (601) 576-7582 prior to shipping any isolate. Confirmatory
tests for some of these results may be obtained by special arrangement through the Epidemiology Program at (601)
576-7725.
Positive Bacterial Cultures or Direct Examinations
Result
Reportable Disease
Anaplasmosis phagocytophilum
Anaplasmosis
Any bacterial agent in CSF
Bacterial meningitis
Bacillus anthracisâ€
Anthrax
Bordetella pertussis
Pertussis
Borrelia burgdorferiâ€
Lyme disease
Brucella speciesâ€
Brucellosis
Burkholderia malleiâ€
Glanders
Burkholderia pseudomalleiâ€
Melioidosis
Campylobacter species
Campylobacteriosis
Carbapenem-resistant Acinetobacter baumanniiâ€
Carbapenem-resistant Acinetobacter baumannii (CRAB)
Carbapenem-resistant Enterobacteriaceae
Carbapenem-resistant Enterobacteriaceae (CRE)
Carbapenem-resistant Pseudomonas aeruginosaâ€
Carbapenem-resistant Pseudomonas aeruginosa (CRPA)
Chlamydia psittaci
Psittacosis
Chlamydia trachomatis
Chlamydia trachomatis genital infection
Clostridium botulinum†**
Botulism
Clostridium tetani
Tetanus
Corynebacterium diphtheriaeâ€
Diphtheria
Coxiella burnetiiâ€
Q fever
Ehrlichia species
Ehrlichiosis
Enterococcus species*, vancomycin resistant
Enterococcus infection, invasive vancomycin resistant
Escherichia coli O157:H7 and any shiga toxin-producing
Escherichia coli O157:H7 and any shiga toxin-
E. coli (STEC)â€
producing E. coli (STEC)
Francisella tularensisâ€
Tularemia
Grimontia hollisaeâ€
Noncholera Vibrio disease
Haemophilus ducreyi
Chancroid
Haemophilus influenza †*(not from throat, sputum)
Haemophilus influenzae infection, invasive
Legionella species
Legionellosis
Listeria monocytogenesâ€
Listeriosis
Mycobacterium species
Nontuberculous mycobacterial disease
Mycobacterium tuberculosisâ€
Tuberculosis
Neisseria gonorrheae
Gonorrhea
Neisseria meningitidis †*
Neisseria meningitidis infection, invasive
Photobacterium damselaeâ€
Noncholera Vibrio disease
Rickettsia prowazekii
Typhus fever
Rickettsia rickettsia
Rocky Mountain spotted fever
Salmonella species, not S. typhiâ€
Salmonellosis
Salmonella typhi â€
Typhoid fever
Shigella speciesâ€
Shigellosis
Staphylococcus aureus- vancomycin resistant or
Staphylococcus aureus vancomycin resistant (VRSA) or
vancomycin intermediate resistant
vancomycin intermediate (VISA)
Streptococcus pneumoniae*†â€
Streptococcus pneumoniae, invasive infection
Vibrio cholerae 01â€
Cholera
Vibrio speciesâ€
Noncholera Vibrio disease
Yersinia pestisâ€
Plague
†Isolates of organism should be sent to the Mississippi State Department of Health Public Health Laboratory. All
referring laboratories should call the Public Health Laboratory at (601) 576-7582 prior to shipping any isolate.
††Isolates should be sent to the Mississippi State Department of Health Public Health Laboratory for specimens
obtained from a normally sterile site in patients ≤12 years of age.
*Specimen obtained from a normally sterile site (usually blood or cerebrospinal fluid, or, less commonly, joint,
pleural, or pericardial fluid). Do not report throat or sputum isolates.
**Contact the Mississippi State Department of Health, Epidemiology Program at (601) 576-7725 or the Public
Health Laboratory (601) 576-7582 for appropriate tests when considering a diagnosis of botulism.
Positive Serologic Tests
Anaplasmosis
Arboviral agents including but not limited to those due to:
California encephalitis virus (IgM)
Chikungunya virus (IgM)
Dengue (IgM)
Eastern equine encephalitis virus (IgM)
LaCrosse virus (IgM)
St. Louis encephalitis virus (IgM)
Western equine encephalitis virus (IgM)
West Nile virus (IgM)
Zika virus
Brucellosis
Chagas Disease (American trypanosomiasis)
Cholera
Chlamydia trachomatis genital infection
Ehrlichiosis (IgM and IgG)
Hepatitis A (anti-HAV IgM)
Hepatitis B (anti-HBcIgM)
Hepatitis B (HBsAg) in pregnancy
Hepatitis C
HIV infection
Legionellosis§ (including urine Ag)
Lyme disease (IgM and IgG, including Western Blot)
Malaria
Measles (IgM)
Mumps (IgM)
M. tuberculosis infection (IGRA)
Plague
Poliomyelitis
Psittacosis
Rocky Mountain spotted fever (IgM and IgG)
Rubella (IgM)
Syphilis
Smallpox
Trichinosis
Varicella infection, primary in patients > 15 years of age
Yellow fever (IgM)
§ Serologic confirmation of an acute case of legionellosis cannot be based on a single titer. There
must be a four-fold rise in titer to >1:128 between acute and convalescent specimens.
Positive Parasitic Cultures or Direct Examinations (including PCR)
Result
Reportable Disease Condition
Any parasite in CSFâ€
Parasitic meningitis
Cryptosporidium parvum
Cryptosporidiosis
Trypanosoma cruzi
Chagas disease (American trypanosomiasis)
Plasmodium speciesâ€
Malaria
Positive Fungal Cultures or Direct Examinations
Result
Reportable Disease Condition
Any fungus in CSF
Fungal meningitis
Candida aurisâ€
Candida auris
Positive Viral Cultures or Direct Examinations (including PCR)
Result
Reportable Disease Condition
Any virus in CSF
Viral meningitis
Arboviral agents including but not limited to:
California encephalitis virus
California encephalitis virus
Chikungunya virus
Chikungunya virus
Dengue virus, serotype 1, 2, 3, or 4
Dengue
Eastern equine encephalomyelitis virus
Eastern equine encephalitis (EEE) virus
LaCrosse virus
LaCrosse encephalitis virus
St. Louis encephalitis virus
St. Louis encephalitis (SLE) virus
Western equine encephalitis virus
Western equine encephalitis (WEE) virus
West Nile virus
West Nile encephalitis (WNV) virus
Zika virus
Zika virus
Arena viruses
Viral hemorrhagic fevers
Filoviruses
Viral hemorrhagic fevers
Hepatitis C RNA (positive and negative
Hepatitis C
results)
Poliovirus, type 1, 2, or 3
Poliomyelitis
Varicella virus
Varicella in patients > 15 years of age
Variola virus
Smallpox
Yellow fever virus
Yellow fever
Positive Blood Chemistries
ALL blood lead test results in patients less than or equal to 6 years of age are reportable to the
MSDH Lead Program at (601) 576-7447.
Positive Toxin Identification
Ricin toxin from Ricinus communis (castor beans)
Shiga toxin (Escherichia coli)
Surgical Pathology Results
All parasites
Creutzfeldt-Jakob Disease, including new variant
Hansen disease (Mycobacterium leprae)
Human rabies
Malignant Neoplasms
Mycobacterial disease including Tuberculosis
Trichinosis
Acid Fast Bacilli Smears
Any smear positive for acid-fast bacillus (Tuberculosis)