R66-31-8. Residual Solvent Standards

(1) A sample and related batch of cannabinoid product fails quality assurance testing for residual solvents if the results exceed the limits provided in Table 4 unless the solvent is: (a) a component of the product formulation; (b) listed as an ingredient; and (c) generally considered to be safe for the intended form of use. TABLE 4 List of Solvents and Action Levels Solvent Chemical Abstract Service Action level (CAS)Registry number Ppm 1,2 Dimethoxyethane 110-71-4 100 1,4 Dioxane 123-9 380 1-Butanol 71-36-3 5,000 1-Pentanol 71-41-0 5,000 1-Propanol 71-23-8 5,000 2-Butanol 78-92-2 5,000 2-Butanone 78-93-3 5,000 2-Ethoxyethanol 110-80-5 160 2-methylbutane 78-78-4 5,000 2-Propanol (IPA) 67-63-0 5,000 Acetone 67-64-1 5,000 Acetonitrile 75-05-8 410 Benzene 71-43-2 2 Butane 106-97-8 5,000 Cumene 98-82-8 70 Cyclohexane 110-82-7 3,880 Dichloromethane 75-09-2 600 2,2-dimethylbutane 75-83-2 290 2,3-dimethylbutane 79-29-8 290 1,2-dimethylbenzene 95-47-6 See Xylenes 1,3-dimethylbenzene 108-38-3 See Xylenes 1,4-dimethylbenzene 106-42-3 See Xylenes Dimethyl sulfoxide 67-68-5 5,000 Ethanol 64-17-5 5,000 Ethyl acetate 141-78-6 5,000 Ethylbenzene 100-41-4 See Xylenes Ethyl ether 60-29-7 5,000 Ethylene glycol 107-21-1 620 Ethylene Oxide 75-21-8 50 Heptane 142-82-5 5,000 n-Hexane 110-54-3 290 Isopropyl acetate 290 5,000 Methanol 67-56-1 3,000 Methylpropane 75-28-5 5,000 2-Methylpentane 107-83-5 290 3-Methylpentane 96-14-0 290 N,N-dimethylacetamide 127-19-5 1,090 N,N-dimethylformamide 68-12-2 880 Pentane 109-66-0 5,000 Propane 74-98-6 5,000 Pyridine 110-86-1 100 Sulfolane 126-33-0 160 Tetrahydrofuran 109-99-9 720 Toluene 108-88-3 890 Xylenes 1330-20-7 2,170 (2) Xylenes is a combination of the following: (a) 1,2-dimethylbenzene; (b) 1,3-dimethylbenzene; (c) 1,4-dimethylbenzene; and (d) ethyl benzene.